ALDH5A1 and MAGEA11

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		ALDH5A1	MAGEA11
Gene Name		aldehyde dehydrogenase 5 family, member A1	melanoma antigen family A, 11
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Aldehyde Dehydrogenase (NAD) Activity Succinate-semialdehyde Dehydrogenase (NAD+) Activity Succinate-semialdehyde Dehydrogenase [NAD(P)+] Activity Protein Homodimerization Activity	Protein Binding
	Biological Process	Glucose Metabolic Process Acetate Metabolic Process Succinate Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Glycerophospholipid Metabolic Process Glucosylceramide Metabolic Process Galactosylceramide Metabolic Process Glutathione Metabolic Process Synaptic Transmission Neurotransmitter Secretion Central Nervous System Development Gamma-aminobutyric Acid Catabolic Process Post-embryonic Development Respiratory Electron Transport Chain Neurotransmitter Catabolic Process Short-chain Fatty Acid Metabolic Process Protein Homotetramerization
Pathways		Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		Succinic acid NADH Valproic Acid Chlormerodrin
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		2 interactors: ABAT MAGEA11	86 interactors: ACMSD ACTN1 AKR1C3 ALDH5A1 AR ARHGAP29 BCL2L11 BEX2 BIRC2 C18orf54 CCDC14 CCDC146 CCDC185 CDC20B CDKN2B CEP76 CLUAP1 COX7A2L CSNK2A1 DIEXF DNAJC10 DOCK10 ENOX2 EWSR1 FAM156A GNPDA1 HOXB5 IL11 IL6ST ILF3 JADE3 KIAA0408 LNX1 MAPK3 MCRS1 MED28 MGME1 MLF1 MTA1 MXD3 MYOZ1 NCOA2 NDEL1 NDUFAF1 NDUFB9 NIF3L1 NOL4 NOS3 NSUN4 OTUB2 PCBD2 PDE4B PHYH PIN4 PNKD PNKP POLR1D PRDX3 PRKRIP1 PSMF1 RADIL RBM23 SH2D4A SNX20 SNX7 STAR TCEA2 TCEANC TCF25 TEX37 THEM5 TMEM123 TPM3 TRIM27 TRIM51 TRMT1 TXN2 UBE2D4 USP20 VTA1 WDYHV1 WTAP ZBTB16 ZCCHC12 ZNF655 ZSWIM2
Entrez ID		7915	4110
HPRD ID		08361	02281
Ensembl ID		ENSG00000112294	ENSG00000185247
Uniprot IDs		P51649 Q546H9	G5E962 P43364
PDB IDs		2W8N 2W8O 2W8P 2W8Q 2W8R
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid Catabolic Process Gamma-aminobutyric Acid Metabolic Process Behavioral Response To Cocaine Neurotransmitter Catabolic Process Copulation Neurotransmitter Metabolic Process Response To Iron Ion Response To Nicotine Negative Regulation Of Blood Pressure Response To Cocaine Mating Response To Ammonium Ion Neurotransmitter Secretion Cellular Amino Acid Catabolic Process Regulation Of Neurotransmitter Levels Response To Ethanol Response To Alkaloid Adult Behavior Neurotransmitter Transport Regulation Of Blood Pressure Carboxylic Acid Catabolic Process Locomotory Behavior Response To Hypoxia Blood Circulation Response To Metal Ion Single-organism Behavior Cellular Amino Acid Metabolic Process Response To Inorganic Substance Secretion By Cell Response To Drug Monocarboxylic Acid Metabolic Process Synaptic Transmission Behavior Secretion	Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Metabolic Process RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Regulation Of Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Gene Expression Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Catabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Apoptotic Process Metabolic Process Protein Polyubiquitination Negative Regulation Of Cellular Protein Metabolic Process Cellular Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Testosterone Biosynthetic Process Regulation Of Cell Death Macromolecule Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Protein Metabolic Process Rhythmic Process Cell Death Response To Lipopolysaccharide Death Negative Regulation Of Protein Metabolic Process Respiratory Electron Transport Chain Response To Molecule Of Bacterial Origin Regulation Of Cell Cycle Electron Transport Chain Oxidation-reduction Process Negative Regulation Of Catalytic Activity RNA Methylation Histone H4-K5 Acetylation Histone H4-K8 Acetylation Apoptotic Process Reproductive Structure Development Positive Regulation Of Gene Expression Reproductive System Development Negative Regulation Of Mitotic Cell Cycle Phase Transition Programmed Cell Death
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