ALDH5A1 and ABAT

Number of citations of the paper that reports this interaction (PMID 6470007)
3

Data Source:
HPRD (in vitro)

		ALDH5A1	ABAT
Gene Name		aldehyde dehydrogenase 5 family, member A1	4-aminobutyrate aminotransferase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix	Mitochondrion Mitochondrial Matrix 4-aminobutyrate Transaminase Complex Neuron Projection Extracellular Vesicular Exosome
	Molecular Function	Aldehyde Dehydrogenase (NAD) Activity Succinate-semialdehyde Dehydrogenase (NAD+) Activity Succinate-semialdehyde Dehydrogenase [NAD(P)+] Activity Protein Homodimerization Activity	4-aminobutyrate Transaminase Activity Pyridoxal Phosphate Binding Succinate-semialdehyde Dehydrogenase Binding Protein Homodimerization Activity (S)-3-amino-2-methylpropionate Transaminase Activity
	Biological Process	Glucose Metabolic Process Acetate Metabolic Process Succinate Metabolic Process Glutamate Metabolic Process Glutamine Metabolic Process Glycerophospholipid Metabolic Process Glucosylceramide Metabolic Process Galactosylceramide Metabolic Process Glutathione Metabolic Process Synaptic Transmission Neurotransmitter Secretion Central Nervous System Development Gamma-aminobutyric Acid Catabolic Process Post-embryonic Development Respiratory Electron Transport Chain Neurotransmitter Catabolic Process Short-chain Fatty Acid Metabolic Process Protein Homotetramerization	Response To Hypoxia Synaptic Transmission Neurotransmitter Secretion Copulation Locomotory Behavior Gamma-aminobutyric Acid Catabolic Process Response To Iron Ion Response To Nicotine Neurotransmitter Catabolic Process Response To Drug Response To Ethanol Negative Regulation Of Blood Pressure Behavioral Response To Cocaine
Pathways		Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses	Neurotransmitter Release Cycle Degradation of GABA GABA synthesis, release, reuptake and degradation Transmission across Chemical Synapses
Drugs		Succinic acid NADH Valproic Acid Chlormerodrin	Pyridoxal Phosphate Pyruvic acid L-Glutamic Acid L-Alanine Valproic Acid Phenelzine Vigabatrin (4e)-4-Aminohex-4-Enoic Acid 4-Amino Hexanoic Acid
Diseases
GWAS		Liver enzyme levels (alkaline phosphatase) ( 22001757)
Protein-Protein Interactions		2 interactors: ABAT MAGEA11	1 interactors: ALDH5A1
Entrez ID		7915	18
HPRD ID		08361	00661
Ensembl ID		ENSG00000112294	ENSG00000183044
Uniprot IDs		P51649 Q546H9	P80404
PDB IDs		2W8N 2W8O 2W8P 2W8Q 2W8R
Enriched GO Terms of Interacting Partners?		Gamma-aminobutyric Acid Catabolic Process Gamma-aminobutyric Acid Metabolic Process Behavioral Response To Cocaine Neurotransmitter Catabolic Process Copulation Neurotransmitter Metabolic Process Response To Iron Ion Response To Nicotine Negative Regulation Of Blood Pressure Response To Cocaine Mating Response To Ammonium Ion Neurotransmitter Secretion Cellular Amino Acid Catabolic Process Regulation Of Neurotransmitter Levels Response To Ethanol Response To Alkaloid Adult Behavior Neurotransmitter Transport Regulation Of Blood Pressure Carboxylic Acid Catabolic Process Locomotory Behavior Response To Hypoxia Blood Circulation Response To Metal Ion Single-organism Behavior Cellular Amino Acid Metabolic Process Response To Inorganic Substance Secretion By Cell Response To Drug Monocarboxylic Acid Metabolic Process Synaptic Transmission Behavior Secretion	Gamma-aminobutyric Acid Catabolic Process Acetate Metabolic Process Glucosylceramide Metabolic Process Succinate Metabolic Process Neurotransmitter Catabolic Process Gamma-aminobutyric Acid Metabolic Process Short-chain Fatty Acid Metabolic Process Galactosylceramide Metabolic Process Glutamate Metabolic Process Glycosylceramide Metabolic Process Neurotransmitter Metabolic Process Glutamine Metabolic Process Protein Homotetramerization Glutathione Metabolic Process Glycosphingolipid Metabolic Process Ceramide Metabolic Process Dicarboxylic Acid Metabolic Process Protein Tetramerization Neurotransmitter Secretion Respiratory Electron Transport Chain Cellular Amino Acid Catabolic Process Electron Transport Chain Glycolipid Metabolic Process Regulation Of Neurotransmitter Levels Post-embryonic Development Glucose Metabolic Process Peptide Metabolic Process Sphingolipid Metabolic Process Neurotransmitter Transport Cellular Respiration Carboxylic Acid Catabolic Process Hexose Metabolic Process Membrane Lipid Metabolic Process Cellular Modified Amino Acid Metabolic Process Monosaccharide Metabolic Process Cellular Amide Metabolic Process Protein Homooligomerization Alpha-amino Acid Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Glycerophospholipid Metabolic Process Fatty Acid Metabolic Process Sulfur Compound Metabolic Process Glycerolipid Metabolic Process Phospholipid Metabolic Process Generation Of Precursor Metabolites And Energy Protein Oligomerization Cellular Amino Acid Metabolic Process Secretion By Cell Monocarboxylic Acid Metabolic Process Synaptic Transmission
Tagcloud ?			16p13 2p13 3p13 anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 rbfox1 spanning tmem114 vertebral
Tagcloud (Difference) ?			16p13 2p13 3p13 anomalies cgh cytogenetic determining difficulties disability duplicated duplication duplications dysmorphisms epilepsy facial girl grin2a hotspot intellectual litaf microdeletions novo omim overlapping pmm2 rbfox1 spanning tmem114 vertebral
Tagcloud (Intersection) ?