ALG12 and RPL13A

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ALG12	RPL13A
Gene Name		ALG12, alpha-1,6-mannosyltransferase	ribosomal protein L13a
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Integral Component Of Membrane	Nucleus Cytosol Focal Adhesion Large Ribosomal Subunit Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex GAIT Complex
	Molecular Function	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol Alpha-1,6-mannosyltransferase Activity	Structural Constituent Of Ribosome Poly(A) RNA Binding
	Biological Process	Protein Folding Protein N-linked Glycosylation Dolichol-linked Oligosaccharide Biosynthetic Process Protein N-linked Glycosylation Via Asparagine Post-translational Protein Modification Cellular Protein Metabolic Process Mannosylation	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Negative Regulation Of Translation Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process Cellular Response To Interferon-gamma Negative Regulation Of Formation Of Translation Preinitiation Complex
Pathways		Defective ALG2 causes ALG2-CDG (CDG-1i) Diseases of glycosylation Defective ALG3 causes ALG3-CDG (CDG-1d) Post-translational protein modification Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2 Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS) Defective MGAT2 causes MGAT2-CDG (CDG-2a) Defective ALG1 causes ALG1-CDG (CDG-1k) Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) Defective MOGS causes MOGS-CDG (CDG-2b) Defective ALG6 causes ALG6-CDG (CDG-1c) Defective RFT1 causes RFT1-CDG (CDG-1n) Asparagine N-linked glycosylation Defective ALG8 causes ALG8-CDG (CDG-1h) Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein Defective ALG9 causes ALG9-CDG (CDG-1l) Defective MAN1B1 causes MRT15 Defective MPDU1 causes MPDU1-CDG (CDG-1f) Defective ALG12 causes ALG12-CDG (CDG-1g) Diseases associated with N-glycosylation of proteins Defective ALG11 causes ALG11-CDG (CDG-1p)	Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS			Hematological and biochemical traits ( 20139978)
Protein-Protein Interactions		2 interactors: PRDX4 RPL13A	13 interactors: ALDH2 ALG12 CALM1 CRP CYP2E1 ETS1 FBXO18 FNTA GOLM1 ND1 RPL30 STOM VTN
Entrez ID		79087	23521
HPRD ID		06189	11775
Ensembl ID			ENSG00000142541
Uniprot IDs		Q9BV10	P40429 Q8J015
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Formation Of Translation Preinitiation Complex Negative Regulation Of Male Germ Cell Proliferation Regulation Of Male Germ Cell Proliferation Protein Maturation By Protein Folding I-kappaB Phosphorylation Negative Regulation Of Translational Initiation 4-hydroxyproline Metabolic Process	Regulation Of Rhodopsin Mediated Signaling Pathway Response To Inorganic Substance Rhodopsin Mediated Signaling Pathway Positive Regulation Of Tubulin Deacetylation Regulation Of Acid-sensing Ion Channel Activity Regulation Of Cation Channel Activity Phototransduction, Visible Light Detection Of Visible Light Positive Regulation Of Protein Modification Process Cellular Response To Light Stimulus Phototransduction Positive Regulation Of Cellular Metabolic Process Detection Of Light Stimulus Catabolic Process Response To Calcium Ion Nucleus Organization Response To Intra-S DNA Damage Checkpoint Signaling Protein Farnesylation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Response To Abiotic Stimulus Positive Regulation Of Cellular Protein Metabolic Process Xenobiotic Metabolic Process Cellular Response To Xenobiotic Stimulus Cellular Response To Radiation Response To Ethanol Regulation Of Tubulin Deacetylation PML Body Organization Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Response To Xenobiotic Stimulus Positive Regulation Of Deacetylase Activity Monoterpenoid Metabolic Process Response To Ozone Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Positive Regulation Of Protein Metabolic Process Synaptic Transmission Wound Healing Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Detection Of Abiotic Stimulus Immune Response Regulation Of Immune System Process Negative Regulation Of Vasodilation Neurotransmitter Receptor Metabolic Process Protein Geranylgeranylation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Ethanol Catabolic Process Response To Reactive Oxygen Species Positive Regulation Of Superoxide Anion Generation
Tagcloud ?		bones cardiomyopathy cdg cdgs dislocations dolichol dysplasia dysplasias equinovarus exome frameshifts glycosylation hypoplasia ig infant knees neurodevelopmental oligosaccharides ossification platyspondyly pseudodiastrophic pubic resembles rhizomelic stature talipes underossification undiagnosed vertebrae	aleyrodidae bemisia bestkeeper cyclophilin cyp1 developmentally ef1a gapdh gennadius genorm glyceraldehyde hemiptera normalisation normfinder orthologs qpcr realtime selecting sented suitability tabaci thermal transcript tub1a utilising vitellogenin whiteflies whitefly
Tagcloud (Difference) ?		bones cardiomyopathy cdg cdgs dislocations dolichol dysplasia dysplasias equinovarus exome frameshifts glycosylation hypoplasia ig infant knees neurodevelopmental oligosaccharides ossification platyspondyly pseudodiastrophic pubic resembles rhizomelic stature talipes underossification undiagnosed vertebrae	aleyrodidae bemisia bestkeeper cyclophilin cyp1 developmentally ef1a gapdh gennadius genorm glyceraldehyde hemiptera normalisation normfinder orthologs qpcr realtime selecting sented suitability tabaci thermal transcript tub1a utilising vitellogenin whiteflies whitefly
Tagcloud (Intersection) ?