RBPMS2 and RBM41

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBPMS2	RBM41
Description		RNA binding protein, mRNA processing factor 2	RNA binding motif protein 41
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule	U12-type Spliceosomal Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity	Nucleic Acid Binding RNA Binding Protein Binding U12 SnRNA Binding Pre-mRNA Intronic Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation	MRNA Splicing, Via Spliceosome
Pathways
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		68 interacting genes: ACTMAP AOC1 ARID5A BHLHE40 BOLL C10orf55 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA SPMIP9 STRBP TENT5B TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C	32 interacting genes: BICD2 CCDC85B CCHCR1 CCNC CEP76 DISC1 GOLGA2 HNRNPC HNRNPK HOOK2 HSF2BP KIFC3 KRT27 KRT40 LZTS2 MEOX1 MIPOL1 MKRN3 MTUS2 NFKBID NINL PNMA1 RALYL RBPMS2 RINT1 SPAG5 TGM5 TRAF1 TRAF2 TRIM27 TRIM54 ZBTB10
Entrez ID		348093	55285
HPRD ID		18601	06515
Ensembl ID		ENSG00000166831	ENSG00000089682
Uniprot IDs		Q6ZRY4	A0A8I5KYC8 Q96IZ5
PDB IDs		2M9K	2CPX
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Negative Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Primary Metabolic Process Negative Regulation Of RNA Catabolic Process Intermediate Filament Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Protein Binding Ribonucleoprotein Complex Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression DNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II	Microtubule Cytoskeleton Centrosome Identical Protein Binding Microtubule Binding Microtubule-based Process Microtubule Cytoskeleton Organization Cytoskeleton Organization Thioesterase Binding Cytoplasm Microtubule Anchoring At Microtubule Organizing Center
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