RBPMS2 and RBM42

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RBPMS2	RBM42
Description		RNA binding protein, mRNA processing factor 2	RNA binding motif protein 42
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GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm U4/U6 X U5 Tri-snRNP Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding Identical Protein Binding Protein Homodimerization Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of BMP Signaling Pathway Embryonic Digestive Tract Morphogenesis Positive Regulation Of Smooth Muscle Cell Proliferation Negative Regulation Of Smooth Muscle Cell Differentiation	MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome
Pathways			mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Electrocardiogram morphology (amplitude at temporal datapoints) ( 32916098) Neuroticism ( 29255261) Platelet count ( 32888494) PR interval ( 32439900)
Interacting Genes		68 interacting genes: ACTMAP AOC1 ARID5A BHLHE40 BOLL C10orf55 CAMK2A CBX2 CELF4 DND1 ESRP1 FAM168A FOXD4L1 FOXD4L3 FOXH1 FUBP3 HNRNPC HNRNPK HNRNPU IFIT2 KLF1 KLHDC7B KRTAP11-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP6-1 KRTAP6-2 KRTAP8-1 LASP1 MAGED1 MKRN3 MSX2 MYPOP PATZ1 PCBP1 PPP1R37 PRR20A PRR20B PRR20C PRR20D PRR20E PTBP2 RALY RBFOX1 RBFOX2 RBM3 RBM41 RBM42 RBM46 RBPMS RHOXF2 SEMA3B SNRPA SPMIP9 STRBP TENT5B TIAL1 UFSP1 UNC119 USP54 VHL VPS37C ZBTB32 ZC3H10 ZMAT5 ZNF34 ZNF385C	23 interacting genes: APP BAG4 CEP55 DMRTB1 FHL3 HNRNPK OGT PCBP1 PPIL1 PRR20A PRR20B PRR20C PRR20D PRR20E QKI RBFOX2 RBM4 RBPMS RBPMS2 SFSWAP SNRPA TRNAU1AP WBP4
Entrez ID		348093	79171
HPRD ID		18601	11303
Ensembl ID		ENSG00000166831	ENSG00000126254
Uniprot IDs		Q6ZRY4	Q9BTD8
PDB IDs		2M9K	6QW6 6QX9 8H6E 8H6J 8QP8 8QP9 8QPK 8QXD 8R08 8R0A
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding Regulation Of MRNA Metabolic Process Negative Regulation Of MRNA Metabolic Process RNA Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Spliceosomal Complex Negative Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Stabilization MRNA Metabolic Process Negative Regulation Of MRNA Catabolic Process RNA Stabilization RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Regulation Of Primary Metabolic Process Negative Regulation Of RNA Catabolic Process Intermediate Filament Negative Regulation Of RNA Splicing Regulation Of Gene Expression Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Stability Regulation Of Macromolecule Biosynthetic Process MRNA 3'-UTR Binding Protein Binding Ribonucleoprotein Complex Regulation Of RNA Stability Regulation Of Macromolecule Metabolic Process Pre-mRNA Binding Negative Regulation Of Macromolecule Metabolic Process Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Post-transcriptional Regulation Of Gene Expression DNA Binding Regulation Of MiRNA-mediated Gene Silencing Regulation Of Post-transcriptional Gene Silencing Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Metabolic Process RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleic Acid Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Splicing MRNA Binding MRNA Processing RNA Binding Cytoplasmic Stress Granule MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process RNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Metabolic Process RNA Metabolic Process Spliceosomal Complex Pre-mRNA Intronic Binding Regulation Of Translation Pre-mRNA Binding Nucleus Negative Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing MRNA 3'-UTR Binding Nucleic Acid Metabolic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Post-transcriptional Regulation Of Gene Expression MiRNA Binding Cap-independent Translational Initiation IRES-dependent Translational Initiation Of Linear MRNA Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Internal N(7)-methylguanine-containing RNA Reader Activity Negative Regulation Of MRNA Modification Negative Regulation Of Translational Initiation Negative Regulation Of RNA Metabolic Process Negative Regulation Of Translation
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