CACNA1B and CACNB3

Number of citations of the paper that reports this interaction (PMID 12161429)
18

Data Source:
HPRD (in vitro)

		CACNA1B	CACNB3
Gene Name		calcium channel, voltage-dependent, N type, alpha 1B subunit	calcium channel, voltage-dependent, beta 3 subunit
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane Voltage-gated Calcium Channel Complex Dendrite Neuronal Cell Body	Cytosol Voltage-gated Calcium Channel Complex Membrane Apical Plasma Membrane
	Molecular Function	Voltage-gated Calcium Channel Activity Calcium Ion Binding Protein Binding ATP Binding Protein C-terminus Binding High Voltage-gated Calcium Channel Activity	Voltage-gated Calcium Channel Activity High Voltage-gated Calcium Channel Activity Protein Kinase Binding
	Biological Process	Transport Synaptic Transmission Neurotransmitter Secretion Locomotory Behavior Regulation Of Heart Contraction Regulation Of Blood Pressure Regulation Of Ion Transmembrane Transport Response To Pain Membrane Depolarization Regulation Of Calcium Ion Transport Calcium Ion Import Calcium Ion Transmembrane Transport Membrane Depolarization During Action Potential	Transport Calcium Ion Transport Synaptic Transmission Axon Guidance Neuromuscular Junction Development T Cell Receptor Signaling Pathway Membrane Depolarization Calcium Ion Transmembrane Transport Regulation Of Voltage-gated Calcium Channel Activity
Pathways		Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Transmission across Chemical Synapses	NCAM1 interactions Axon guidance Integration of energy metabolism Regulation of insulin secretion NCAM signaling for neurite out-growth Depolarization of the Presynaptic Terminal Triggers the Opening of Calcium Channels Transmission across Chemical Synapses Adrenaline,noradrenaline inhibits insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: APBA1 CACNB3 GNAO1 GNB1 PDLIM5 PPM1A RGS12 RIMS1 RXRB	4 interactors: CACNA1B CACNA1C FASLG SYT1
Entrez ID		774	784
HPRD ID		03005	11879
Ensembl ID		ENSG00000148408	ENSG00000167535
Uniprot IDs		B1AQK4 B1AQK7 Q00975	P54284
PDB IDs		2LCM
Enriched GO Terms of Interacting Partners?		Glutamate Secretion Synaptic Transmission Dopamine Receptor Signaling Pathway Signaling Cell Communication Acid Secretion Cell-cell Signaling Dicarboxylic Acid Transport Membrane Depolarization Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Cellular Response To Hormone Stimulus G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Gamma-aminobutyric Acid Secretion System Development Amino Acid Transport Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of SMAD Protein Complex Assembly Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Cellular Response To Acid Chemical Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Regulation Of Calcium Ion Transport Cardiac Muscle Cell Apoptotic Process Muscle Cell Apoptotic Process Response To Organonitrogen Compound Multicellular Organismal Development DNA-templated Transcription, Initiation Calcium Ion-dependent Exocytosis Of Neurotransmitter N-terminal Protein Myristoylation Locomotory Behavior Gamma-aminobutyric Acid Transport Protein Myristoylation Anatomical Structure Development Response To Organic Cyclic Compound Response To Hormone Regulation Of Membrane Potential Positive Regulation Of Metabolic Process Peptidyl-threonine Dephosphorylation Signal Transduction Cellular Response To Prostaglandin E Stimulus Regulation Of Inhibitory Postsynaptic Membrane Potential G-protein Coupled Acetylcholine Receptor Signaling Pathway Carboxylic Acid Transport Organic Acid Transport Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Developmental Process Negative Regulation Of NF-kappaB Import Into Nucleus Nervous System Development Cellular Response To Prostaglandin Stimulus	Cell-cell Signaling Calcium Ion Import Membrane Depolarization During Action Potential Secretion By Cell Synaptic Transmission Secretion Action Potential Neurotransmitter Secretion Membrane Depolarization Fast, Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Neurotransmitter Levels Neurotransmitter Transport Regulation Of Heart Contraction Regulation Of Blood Pressure Regulation Of Calcium Ion Transport Calcium Ion Transmembrane Transport Smooth Muscle Contraction Involved In Micturition Calcium-mediated Signaling Using Extracellular Calcium Source Endosomal Lumen Acidification Locomotory Behavior Retinal Cell Programmed Cell Death Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Membrane Potential Necroptotic Signaling Pathway Calcium Ion Transport Blood Circulation Micturition Exocytosis Cellular Chloride Ion Homeostasis Inflammatory Cell Apoptotic Process Chloride Ion Homeostasis Ion Transport Urinary Bladder Smooth Muscle Contraction Regulation Of Ion Transmembrane Transport Positive Regulation Of Endothelial Cell Apoptotic Process Growth Hormone Secretion Detection Of Calcium Ion Cell Communication By Electrical Coupling Involved In Cardiac Conduction Cellular Cation Homeostasis Cellular Ion Homeostasis Establishment Of Localization In Cell Positive Regulation Of Calcium Ion-dependent Exocytosis Cell Communication By Electrical Coupling Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion T Cell Apoptotic Process Cellular Chemical Homeostasis Positive Regulation Of Vesicle Fusion Signaling Ion Homeostasis Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
Tagcloud ?		annealed arguably asd autism bd bipolar candidates chip cnvs disparate fgfr1 glycogen gsk3beta gwass incorporated investigators lithium microarrays nrng pathophysiology pcdh9 phosphoinositide revolving salts searches seemingly shortcomings snap29 sz	acinus adapter alg2 casp3 coinduction competing elucidating ercc3 fem1 gadd153 gadd34 gated gsn helps hereditary heretofore igf1 igfbp2 ischemia modules muscular nrp1 oligodeoxynucleotide permits smn1 tfdp1 tiar vim
Tagcloud (Difference) ?		annealed arguably asd autism bd bipolar candidates chip cnvs disparate fgfr1 glycogen gsk3beta gwass incorporated investigators lithium microarrays nrng pathophysiology pcdh9 phosphoinositide revolving salts searches seemingly shortcomings snap29 sz	acinus adapter alg2 casp3 coinduction competing elucidating ercc3 fem1 gadd153 gadd34 gated gsn helps hereditary heretofore igf1 igfbp2 ischemia modules muscular nrp1 oligodeoxynucleotide permits smn1 tfdp1 tiar vim
Tagcloud (Intersection) ?