TRIM26 and RNF126

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		TRIM26	RNF126
Gene Name		tripartite motif containing 26	ring finger protein 126
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Cytosol	Nucleus Cytoplasm
	Molecular Function	DNA Binding Zinc Ion Binding Metal Ion Binding	Epidermal Growth Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity
	Biological Process	Cytokine-mediated Signaling Pathway Innate Immune Response Negative Regulation Of Viral Entry Into Host Cell Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Release From Host Cell	Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Retrograde Transport, Endosome To Golgi Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process
Pathways		Interferon gamma signaling Interferon Signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Schizophrenia ( 21926974 22883433)
Protein-Protein Interactions		15 interactors: AES MNAT1 OTUB2 PHF7 RABEP1 RNF10 RNF126 THAP1 TRIM41 UBE2D1 UBE2D2 UBE2D3 USP36 USP39 USP5	26 interactors: AICDA BAG6 CDKN1A CSNK2B EGFR HMGCL MDM2 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N USP15 USP2
Entrez ID		7726	55658
HPRD ID		02901	11501
Ensembl ID		ENSG00000234127	ENSG00000070423
Uniprot IDs		Q12899	A8K0Q1 Q9BV68
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Protein K48-linked Ubiquitination Modification-dependent Protein Catabolic Process Cellular Macromolecule Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Catabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Ubiquitination Proteolysis Protein Modification By Small Protein Conjugation Cellular Protein Modification Process Cellular Protein Metabolic Process Catabolic Process Protein Polyubiquitination Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Regulation Of DNA-templated Transcription In Response To Stress TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Toll-like Receptor 4 Signaling Pathway Protein Metabolic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein Deubiquitination Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Protein K48-linked Deubiquitination Protein Modification By Small Protein Removal Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Transcription Initiation From RNA Polymerase II Promoter Cellular Metabolic Process Positive Regulation Of Innate Immune Response Regulation Of Proteasomal Protein Catabolic Process Protein Monoubiquitination DNA-templated Transcription, Initiation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Innate Immune Response Response To Hypoxia Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process BMP Signaling Pathway RNA Metabolic Process Transcription, DNA-templated Cellular Response To Stress Regulation Of Protein Catabolic Process RNA Biosynthetic Process	Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Catabolic Process Proteolysis Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Polyubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K48-linked Ubiquitination Immune System Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Cell Cycle Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition Immune Response-regulating Signaling Pathway Immune Response Positive Regulation Of Cell Cycle Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity
Tagcloud ?			cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Difference) ?			cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Intersection) ?