RNF126 and TRIM52

Number of citations of the paper that reports this interaction (PMID 22493164)
2

Data Source:
BioGRID (two hybrid)

		RNF126	TRIM52
Gene Name		ring finger protein 126	tripartite motif containing 52
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Intracellular
	Molecular Function	Epidermal Growth Factor Receptor Binding Protein Binding Zinc Ion Binding Ligase Activity Ubiquitin Protein Ligase Activity	Zinc Ion Binding
	Biological Process	Protein Monoubiquitination Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Cell Proliferation Retrograde Transport, Endosome To Golgi Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein K48-linked Ubiquitination Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process	Positive Regulation Of NF-kappaB Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		26 interactors: AICDA BAG6 CDKN1A CSNK2B EGFR HMGCL MDM2 NUDT3 OTUB1 OTUB2 PLK1 PSMF1 RBX1 SNUPN TRIM11 TRIM23 TRIM26 TRIM52 TSG101 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2N USP15 USP2	5 interactors: APP NEDD4 RNF114 RNF126 TRIM41
Entrez ID		55658	84851
HPRD ID		11501	10283
Ensembl ID		ENSG00000070423
Uniprot IDs		A8K0Q1 Q9BV68	L0CQ38 Q96A61
PDB IDs
Enriched GO Terms of Interacting Partners?		Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Cellular Protein Modification Process Protein Catabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Cellular Macromolecule Catabolic Process Catabolic Process Proteolysis Cellular Protein Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Protein Polyubiquitination Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Protein K48-linked Ubiquitination Immune System Process Innate Immune Response Negative Regulation Of Mitotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Nitrogen Compound Metabolic Process Cellular Response To DNA Damage Stimulus Cellular Metabolic Process Negative Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Cellular Response To Stress Regulation Of Cellular Protein Metabolic Process Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Negative Regulation Of Cell Cycle Response To Stress Regulation Of DNA-templated Transcription In Response To Stress Negative Regulation Of Mitotic Cell Cycle Phase Transition Immune Response-regulating Signaling Pathway Immune Response Positive Regulation Of Cell Cycle Cell Cycle Negative Regulation Of Proteasomal Protein Catabolic Process Mitotic Cell Cycle Checkpoint Regulation Of Gene Expression Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Ligase Activity	Protein Ubiquitination Protein Modification By Small Protein Conjugation Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Protein K63-linked Ubiquitination Protein Monoubiquitination Neuromuscular Junction Development Cellular Protein Modification Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of ERBB Signaling Pathway Regulation Of Synapse Structure Or Activity Cytoplasm-associated Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Transmission Of Virus Development Involved In Symbiotic Interaction Cellular Protein Metabolic Process Synaptic Growth At Neuromuscular Junction Protein Polyubiquitination Synapse Organization Collateral Sprouting In Absence Of Injury Intracellular Receptor Signaling Pathway Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Progesterone Receptor Signaling Pathway Axon Choice Point Recognition Regulation Of Transcription From RNA Polymerase II Promoter In Response To UV-induced DNA Damage Glucocorticoid Receptor Signaling Pathway Neuron Remodeling Response To Light Stimulus Vesicle-mediated Transport Intracellular Transport Protein Targeting To Lysosome Negative Regulation Of Sodium Ion Transport Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Misfolded Or Incompletely Synthesized Protein Catabolic Process Cellular Response To Misfolded Protein Protein Localization To Lysosome Response To Misfolded Protein Response To Radiation Cellular Copper Ion Homeostasis Receptor Catabolic Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Targeting To Vacuole Copper Ion Homeostasis Suckling Behavior Regulation Of Neuron Differentiation Proteolysis Involved In Cellular Protein Catabolic Process
Tagcloud ?		cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Difference) ?		cargo cathepsin cation cholera depleted dispersed e3 endosomal endosomes finger furin internalization lastly ligase lysosomal mannose missorting mpr proteasome rab4 rescue retrograde route sorting tgn38 toxin transiently ubiquitin unaffected
Tagcloud (Intersection) ?