VEZF1 and RUBCN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VEZF1	RUBCN
Description		vascular endothelial zinc finger 1	rubicon autophagy regulator
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleoplasm Lysosome Endosome Early Endosome Late Endosome Golgi Apparatus Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Phosphatidylinositol 3-kinase Inhibitor Activity Phosphatidylinositol Phosphate Binding
	Biological Process	Angiogenesis Endothelial Cell Development Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Immune System Process Endocytosis Phagocytosis Autophagy Negative Regulation Of Autophagy Negative Regulation Of Endocytosis Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Multivesicular Body Sorting Pathway Negative Regulation Of Autophagosome Maturation
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		65 interacting genes: AGR2 ATXN7L1 BANP C10orf55 CEACAM6 CEP76 DAZAP2 EHMT2 FAM153B FAM168B FOSB FSD2 GOLGA6L9 GPSM1 HIVEP1 HOMEZ HSF2BP HSPB2 HSPB2-C11orf52 INCA1 KCTD7 KRT40 KRTAP10-8 KRTAP19-5 KRTAP8-1 LASP1 LCN2 LHX3 LMO2 LZTS2 MEIS3 MEOX2 MLLT10 MSX2 NCKIPSD NFYA NRF1 OGT PFDN5 PICK1 PLAGL2 POGZ POU6F2 PRKAR1B PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS RUBCN SF3A2 SOX13 SP4 SPAG16 TLE5 TRAF1 TRAF2 TRIM27 TSC1 UBE2I VBP1 VPS52 WWOX ZMYND12	18 interacting genes: ANKRD11 BRD1 BYSL DPF2 DRC4 ENKD1 EXOC1 FAM161A FAM9B NME7 PYCARD RNF34 SMAD9 TCEANC VEZF1 ZFYVE21 ZNF250 ZNF648
Entrez ID		7716	9711
HPRD ID		08416	11069
Ensembl ID		ENSG00000136451	ENSG00000145016
Uniprot IDs		J3QSH4 Q14119	A0A9L9PY84 Q8N4U6 Q92622
PDB IDs			6WCW
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Prefoldin Complex Phosphatidylinositol 3-kinase Inhibitor Activity Negative Regulation Of Macroautophagy Intermediate Filament Negative Regulation Of Wnt Signaling Pathway
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