VEZF1 and SOX13

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VEZF1	SOX13
Description		vascular endothelial zinc finger 1	SRY-box transcription factor 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Angiogenesis Endothelial Cell Development Regulation Of Transcription By RNA Polymerase II Cellular Defense Response Positive Regulation Of Endothelial Cell Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Spinal Cord Oligodendrocyte Cell Differentiation Cell Differentiation Gamma-delta T Cell Differentiation Cell Fate Commitment Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation
Pathways			Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Adverse response to drug ( 30420678) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ziprazidone in schizophrenia ( 29503163) Thyroid stimulating hormone levels ( 30843173)
Interacting Genes		65 interacting genes: AGR2 ATXN7L1 BANP C10orf55 CEACAM6 CEP76 DAZAP2 EHMT2 FAM153B FAM168B FOSB FSD2 GOLGA6L9 GPSM1 HIVEP1 HOMEZ HSF2BP HSPB2 HSPB2-C11orf52 INCA1 KCTD7 KRT40 KRTAP10-8 KRTAP19-5 KRTAP8-1 LASP1 LCN2 LHX3 LMO2 LZTS2 MEIS3 MEOX2 MLLT10 MSX2 NCKIPSD NFYA NRF1 OGT PFDN5 PICK1 PLAGL2 POGZ POU6F2 PRKAR1B PRR20A PRR20B PRR20C PRR20D PRR20E RBPMS RUBCN SF3A2 SOX13 SP4 SPAG16 TLE5 TRAF1 TRAF2 TRIM27 TSC1 UBE2I VBP1 VPS52 WWOX ZMYND12	8 interacting genes: INO80B MECOM SMAD7 TRAF2 TXLNB VEZF1 YTHDC1 ZNF587
Entrez ID		7716	9580
HPRD ID		08416	09205
Ensembl ID		ENSG00000136451	ENSG00000143842
Uniprot IDs		J3QSH4 Q14119	Q9UN79
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of DNA-templated Transcription Identical Protein Binding Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Nucleobase-containing Compound Metabolic Process Sequence-specific DNA Binding Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Prefoldin Complex Phosphatidylinositol 3-kinase Inhibitor Activity Negative Regulation Of Macroautophagy Intermediate Filament Negative Regulation Of Wnt Signaling Pathway	Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of T Cell Cytokine Production Regulation Of DNA-templated Transcription Zinc Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Positive Regulation Of Chondrocyte Development Regulation Of T Cell Mediated Immunity TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Primary Follicle Stage Mammalian Oogenesis Stage Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Cytokine Production Involved In Immune Response Protein-containing Complex Disassembly Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex MRNA Alternative Polyadenylation Regulation Of JNK Cascade Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Chondrocyte Proliferation CD27 Signaling Pathway Nucleoplasm Chromatin Remodeling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone H3K9 Monomethyltransferase Activity Activin Receptor Binding Regulation Of Chondrocyte Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Regulation Of Metabolic Process Histone H3K9me2 Methyltransferase Activity Regulation Of Production Of Molecular Mediator Of Immune Response Heteromeric SMAD Protein Complex Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Histone H3K9 Methyltransferase Activity Regulation Of Adaptive Immune Response Thioesterase Binding
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