SOX13 and ZNF587

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SOX13	ZNF587
Description		SRY-box transcription factor 13	zinc finger protein 587
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Spinal Cord Oligodendrocyte Cell Differentiation Cell Differentiation Gamma-delta T Cell Differentiation Cell Fate Commitment Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		Deactivation of the beta-catenin transactivating complex	Generic Transcription Pathway
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ziprazidone in schizophrenia ( 29503163) Thyroid stimulating hormone levels ( 30843173)	Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes ( 29221444)
Interacting Genes		8 interacting genes: INO80B MECOM SMAD7 TRAF2 TXLNB VEZF1 YTHDC1 ZNF587	130 interacting genes: ADAMTSL4 AQP6 ASB15 ASB6 AXIN2 BEGAIN C17orf50 CARD10 CARD9 CCDC125 CCDC136 CCDC85B CEP44 CEP70 CHRDL2 CSRNP1 CYSRT1 DEF8 DHX57 EFEMP2 FCHSD2 FHL3 FHL5 FSD2 FST GOLGA2 GOLGA6L9 GOPC GSC2 HMBOX1 HOOK2 HOXA1 HSF2BP IGFBP6 IKBKG IKZF1 IKZF3 INSC ISY1-RAB43 KATNBL1 KCTD7 KPRP KRT31 KRT38 KRT40 KRTAP1-1 KRTAP1-3 KRTAP10-1 KRTAP10-10 KRTAP10-11 KRTAP10-3 KRTAP10-5 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP12-2 KRTAP12-3 KRTAP2-3 KRTAP2-4 KRTAP5-7 KRTAP5-9 LDOC1 LHX3 LIMS1 LMO3 LRP2BP LZTS1 MCCD1 MDFI MEOX2 MID2 MKRN3 MTUS2 MYF5 NBPF19 NDUFB7 NEK6 NKAPL NOTCH2NLA NR1D2 PBX2 PDE4DIP PLSCR1 PNMA2 PPARA PRDM14 PRICKLE4 PRPF31 RORB RUNDC3A SMAD9 SMYD5 SOX13 SPRED1 SPRY2 SPRY3 SSX2IP STX11 TBC1D26 TCF4 TENM4 TFIP11 TMCC2 TNS2 TRAF1 TRIB3 TRIM23 TRIM27 TRIM36 TRIM37 TRIM41 TRIM54 TSC1 TSGA10 TXK VPS52 VWC2 ZBTB43 ZBTB8A ZGPAT ZIM2 ZKSCAN8 ZNF286A ZNF330 ZNF417 ZNF547 ZNF774 ZNF829 ZNF837 ZRANB1
Entrez ID		9580	84914
HPRD ID		09205	15864
Ensembl ID		ENSG00000143842	ENSG00000198466
Uniprot IDs		Q9UN79	Q96SQ5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of T Cell Cytokine Production Regulation Of DNA-templated Transcription Zinc Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Positive Regulation Of Chondrocyte Development Regulation Of T Cell Mediated Immunity TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Primary Follicle Stage Mammalian Oogenesis Stage Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Cytokine Production Involved In Immune Response Protein-containing Complex Disassembly Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex MRNA Alternative Polyadenylation Regulation Of JNK Cascade Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Chondrocyte Proliferation CD27 Signaling Pathway Nucleoplasm Chromatin Remodeling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone H3K9 Monomethyltransferase Activity Activin Receptor Binding Regulation Of Chondrocyte Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Regulation Of Metabolic Process Histone H3K9me2 Methyltransferase Activity Regulation Of Production Of Molecular Mediator Of Immune Response Heteromeric SMAD Protein Complex Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Histone H3K9 Methyltransferase Activity Regulation Of Adaptive Immune Response Thioesterase Binding	Intermediate Filament Keratin Filament Zinc Ion Binding Protein Binding Identical Protein Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Sequence-specific DNA Binding Regulation Of RNA Metabolic Process DNA-binding Transcription Factor Activity
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