SOX13

Description		SRY-box transcription factor 13
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Identical Protein Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Anatomical Structure Morphogenesis Spinal Cord Oligodendrocyte Cell Differentiation Cell Differentiation Gamma-delta T Cell Differentiation Cell Fate Commitment Regulation Of Gamma-delta T Cell Differentiation Positive Regulation Of Gamma-delta T Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Brown Fat Cell Differentiation
Pathways		Deactivation of the beta-catenin transactivating complex
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Itch intensity from mosquito bite ( 28199695) Itch intensity from mosquito bite adjusted by bite size ( 28199695) Response to cognitive-behavioural therapy in anxiety disorder ( 31123309) Response to ziprazidone in schizophrenia ( 29503163) Thyroid stimulating hormone levels ( 30843173)
Interacting Genes		8 interacting genes: INO80B MECOM SMAD7 TRAF2 TXLNB VEZF1 YTHDC1 ZNF587
Entrez ID		9580
HPRD ID		09205
Ensembl ID		ENSG00000143842
Uniprot IDs		Q9UN79
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of T Cell Cytokine Production Regulation Of DNA-templated Transcription Zinc Ion Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Beta-catenin Destruction Complex Disassembly Positive Regulation Of Chondrocyte Hypertrophy Positive Regulation Of Chondrocyte Development Regulation Of T Cell Mediated Immunity TORC2 Complex Disassembly TRAF2-GSTP1 Complex TORC1 Complex Assembly CD40 Receptor Binding Primary Follicle Stage Mammalian Oogenesis Stage Regulation Of Macromolecule Metabolic Process Metal Ion Binding Regulation Of Cytokine Production Involved In Immune Response Protein-containing Complex Disassembly Sphingolipid Binding IRE1-TRAF2-ASK1 Complex Tumor Necrosis Factor Receptor Superfamily Complex MRNA Alternative Polyadenylation Regulation Of JNK Cascade Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Chondrocyte Proliferation CD27 Signaling Pathway Nucleoplasm Chromatin Remodeling Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Histone H3K9 Monomethyltransferase Activity Activin Receptor Binding Regulation Of Chondrocyte Development Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Tumor Necrosis Factor Binding Tumor Necrosis Factor Receptor Superfamily Binding Regulation Of Metabolic Process Histone H3K9me2 Methyltransferase Activity Regulation Of Production Of Molecular Mediator Of Immune Response Heteromeric SMAD Protein Complex Regulation Of Lymphocyte Mediated Immunity Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Histone H3K9 Methyltransferase Activity Regulation Of Adaptive Immune Response Thioesterase Binding
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