UTRN and PGM5

Number of citations of the paper that reports this interaction (PubMedID 7589238)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		UTRN	PGM5
Description		utrophin	phosphoglucomutase 5
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Dystrophin-associated Glycoprotein Complex Membrane Filopodium Filopodium Membrane Neuromuscular Junction Protein-containing Complex Ciliary Basal Body Sarcolemma Synapse Postsynaptic Membrane Extracellular Exosome Contractile Ring	Stress Fiber Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Spot Adherens Junction Focal Adhesion Cytoplasmic Side Of Plasma Membrane Intercalated Disc Dystrophin-associated Glycoprotein Complex Membrane Z Disc Cell-substrate Junction Sarcolemma Costamere Anchoring Junction
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Protein-containing Complex Binding Metal Ion Binding	Magnesium Ion Binding Phosphoglucomutase Activity Structural Molecule Activity Intramolecular Phosphotransferase Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Synaptic Signaling Regulation Of Sodium Ion Transmembrane Transport	Carbohydrate Metabolic Process Cell Adhesion Striated Muscle Tissue Development Myofibril Assembly
Pathways		EGR2 and SOX10-mediated initiation of Schwann cell myelination Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs		Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Age at first sexual intercourse ( 34211149) Femur bone mineral density x serum urate levels interaction ( 34046847) Heel bone mineral density x serum urate levels interaction ( 34046847) Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737 33830993) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929) Restless legs syndrome in migraine without aura ( 32918390)	Bipolar disorder ( 22925353) Metabolite levels ( 23823483)
Interacting Genes		20 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 PCNT PGM5 PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2	2 interacting genes: DMD UTRN
Entrez ID		7402	5239
HPRD ID		00547	02990
Ensembl ID		ENSG00000152818	ENSG00000154330
Uniprot IDs		P46939 Q5T097 Q6LBS5	Q15124
PDB IDs		1BHD 1QAG 6M5G	7U21
Enriched GO Terms of Interacting Partners?		Dystrophin-associated Glycoprotein Complex Sarcolemma Cytoskeleton Synapse Focal Adhesion Costamere Filopodium Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Synaptic Signaling PDZ Domain Binding Muscle Contraction Actin Binding Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Syntrophin Complex Cell Projection Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cell Communication Muscle System Process Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Cell-matrix Adhesion Structural Constituent Of Muscle Regulation Of Monoatomic Ion Transmembrane Transport Channel Activator Activity Protein-containing Complex Cell-substrate Junction Sarcomere Regulation Of System Process Regulation Of Metal Ion Transport Positive Regulation Of Cell-matrix Adhesion Dystroglycan Binding Structural Molecule Activity Cell-cell Signaling Cytoplasm Vinculin Binding Nitric-oxide Synthase Binding Calmodulin Binding Signaling Regulation Of Heart Contraction Titin Binding Anchoring Junction Regulation Of Monoatomic Ion Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Regulation Of Cell-substrate Adhesion Cytoskeleton Organization Regulation Of Membrane Potential Nuclear Periphery Muscle Cell Development Plasma Membrane	Vinculin Binding Dystrophin-associated Glycoprotein Complex Filopodium Membrane Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Filopodium Sarcolemma Muscle Organ Development Muscle Structure Development Muscle Contraction Postsynaptic Membrane Muscle System Process Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Synaptic Signaling Actin Binding Syntrophin Complex Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Monoatomic Ion Transport Cell-substrate Junction Contractile Ring Regulation Of Skeletal Muscle Contraction By Calcium Ion Signaling Dystroglycan Binding Cell-cell Signaling Signaling Nitric-oxide Synthase Binding Cell Communication Costamere Protein-containing Complex Neuron Projection Terminus Regulation Of Skeletal Muscle Contraction Muscle Cell Cellular Homeostasis Peptide Biosynthetic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Synapse Myosin Binding Response To Muscle Stretch Maintenance Of Blood-brain Barrier Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cardiac Muscle Cell Action Potential Structural Constituent Of Muscle Cardiac Muscle Contraction Motile Cilium Assembly Myofibril Peptide Metabolic Process Animal Organ Development Cytoskeleton System Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?