UTRN and PGM5

Number of citations of the paper that reports this interaction (PMID 7589238)
7

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		UTRN	PGM5
Gene Name		utrophin	phosphoglucomutase 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytoskeleton Plasma Membrane Dystrophin-associated Glycoprotein Complex Membrane Cell Junction Filopodium Filopodium Membrane Neuromuscular Junction Protein Complex Postsynaptic Membrane Extracellular Vesicular Exosome Contractile Ring	Stress Fiber Cytosol Cell-cell Adherens Junction Spot Adherens Junction Focal Adhesion Cytoplasmic Side Of Plasma Membrane Intercalated Disc Dystrophin-associated Glycoprotein Complex Z Disc Sarcolemma Costamere
	Molecular Function	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding	Magnesium Ion Binding Phosphoglucomutase Activity Structural Molecule Activity
	Biological Process	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Regulation Of Sodium Ion Transmembrane Transporter Activity	Glycogen Biosynthetic Process Glucose Metabolic Process Cell Adhesion Galactose Catabolic Process
Pathways
Drugs
Diseases
GWAS			Bipolar disorder ( 22925353)
Protein-Protein Interactions		16 interactors: ACTA1 ACTN2 DAG1 DISC1 DMD DRP2 DTNA DTNB MARCH5 MARK2 PGM5 PTPN12 SNTA1 SNTB1 SNTB2 UBC	2 interactors: DMD UTRN
Entrez ID		7402	5239
HPRD ID		00547	02990
Ensembl ID		ENSG00000152818	ENSG00000154330
Uniprot IDs		P46939 Q6LBS5	Q15124
PDB IDs		1BHD 1QAG
Enriched GO Terms of Interacting Partners?		Muscle Contraction Muscle System Process Actin-myosin Filament Sliding Muscle Filament Sliding Negative Regulation Of Peptidyl-cysteine S-nitrosylation Actin-mediated Cell Contraction Actin Filament-based Movement Movement Of Cell Or Subcellular Component Myotube Cell Development Regulation Of Sodium Ion Transmembrane Transport Cellular Localization Cardiac Muscle Cell Action Potential Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Transporter Activity Regulation Of Membrane Potential Myotube Differentiation Nerve Maturation Regulation Of Vasoconstriction By Circulating Norepinephrine Regulation Of Sodium Ion Transport Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction Positive Regulation Of Ion Transmembrane Transport Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Striated Muscle Contraction Regulation Of Striated Muscle Contraction Action Potential Skeletal Muscle Fiber Adaptation Establishment Of Glial Blood-brain Barrier Calcium-dependent Cell-matrix Adhesion Nerve Development Regulation Of Neuron Projection Development Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Glial Cell Development Positive Regulation Of Neurogenesis Peripheral Nervous System Development Regulation Of Ion Transmembrane Transport Regulation Of Cell Projection Organization Positive Regulation Of Protein Ubiquitination Positive Regulation Of Cell Development Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Skeletal Muscle Tissue Development Regulation Of Ion Transmembrane Transporter Activity Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Transmembrane Transporter Activity Skeletal Muscle Organ Development Microspike Assembly Regulation Of Neuron Differentiation Positive Regulation Of Cellular Protein Catabolic Process	Regulation Of Sodium Ion Transmembrane Transporter Activity Regulation Of Sodium Ion Transmembrane Transport Positive Regulation Of Cell-matrix Adhesion Regulation Of Sodium Ion Transport Regulation Of Cell-matrix Adhesion Positive Regulation Of Cell-substrate Adhesion Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Cell-substrate Adhesion Muscle Contraction Muscle System Process Muscle Organ Development Establishment Of Glial Blood-brain Barrier Negative Regulation Of Peptidyl-cysteine S-nitrosylation Positive Regulation Of Cell Adhesion Regulation Of Ion Transmembrane Transport Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Establishment Of Blood-nerve Barrier Muscle Structure Development Olfactory Nerve Development Regulation Of Skeletal Muscle Contraction Neurotransmitter Receptor Metabolic Process Regulation Of Cell Adhesion Regulation Of Ion Transport Motile Cilium Assembly Positive Regulation Of Sodium Ion Transmembrane Transporter Activity Establishment Of Blood-brain Barrier Positive Regulation Of Sodium Ion Transmembrane Transport Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Voltage-gated Calcium Channel Activity Anatomical Structure Arrangement Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Peptidyl-serine Phosphorylation Muscle Cell Cellular Homeostasis Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Myotube Cell Development Peptide Biosynthetic Process Muscle Filament Sliding Actin-myosin Filament Sliding Positive Regulation Of Sodium Ion Transport Cardiac Muscle Cell Action Potential Actin-mediated Cell Contraction Nucleus Localization Endothelial Cell Development Muscle Fiber Development Positive Regulation Of Ion Transmembrane Transporter Activity Cardiac Muscle Contraction Cranial Nerve Development Positive Regulation Of Transporter Activity
Tagcloud ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs
Tagcloud (Difference) ?		11q13 12p12 12q13 14q21 17q11 18p11 20q11 6q 6q14 6q15 6q24 7q11 8p11 8q21 9p21 9q21 bcs cnas foxo3 kcnb2 mdn1 p12 p13 q13 q23 q24 q25 q34 tsgs
Tagcloud (Intersection) ?