PGM5 and UTRN

Number of citations of the paper that reports this interaction (PubMedID 7589238)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		PGM5	UTRN
Description		phosphoglucomutase 5	utrophin
Image
GO Annotations	Cellular Component	Stress Fiber Cytoplasm Cytosol Cytoskeleton Plasma Membrane Adherens Junction Spot Adherens Junction Focal Adhesion Cytoplasmic Side Of Plasma Membrane Intercalated Disc Dystrophin-associated Glycoprotein Complex Membrane Z Disc Cell-substrate Junction Sarcolemma Costamere Anchoring Junction	Nucleoplasm Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Dystrophin-associated Glycoprotein Complex Membrane Filopodium Filopodium Membrane Neuromuscular Junction Protein-containing Complex Ciliary Basal Body Sarcolemma Synapse Postsynaptic Membrane Extracellular Exosome Contractile Ring
	Molecular Function	Magnesium Ion Binding Phosphoglucomutase Activity Structural Molecule Activity Intramolecular Phosphotransferase Activity	Actin Binding Integrin Binding Protein Binding Zinc Ion Binding Vinculin Binding Protein Kinase Binding Protein-containing Complex Binding Metal Ion Binding
	Biological Process	Carbohydrate Metabolic Process Cell Adhesion Striated Muscle Tissue Development Myofibril Assembly	Positive Regulation Of Cell-matrix Adhesion Muscle Contraction Muscle Organ Development Synaptic Signaling Regulation Of Sodium Ion Transmembrane Transport
Pathways			EGR2 and SOX10-mediated initiation of Schwann cell myelination Formation of the dystrophin-glycoprotein complex (DGC) Formation of the dystrophin-glycoprotein complex (DGC)
Drugs			Zinc Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Bipolar disorder ( 22925353) Metabolite levels ( 23823483)	Age at first sexual intercourse ( 34211149) Femur bone mineral density x serum urate levels interaction ( 34046847) Heel bone mineral density x serum urate levels interaction ( 34046847) Loneliness (multivariate analysis) ( 27629369) Multisite chronic pain ( 31194737 33830993) Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954) Refractive error ( 32231278) Remission after SSRI treatment in MDD or openness ( 29559929) Response to fenofibrate (triglyceride levels) ( 27002377) Response to mepolizumab in severe asthma ( 29229094) Response to SSRI in MDD or openness ( 29559929) Restless legs syndrome in migraine without aura ( 32918390)
Interacting Genes		2 interacting genes: DMD UTRN	20 interacting genes: ACTA1 ACTN2 C1QTNF9 CALM1 DAG1 DISC1 DMD DRP2 DTNA DTNB ITGB1BP1 MARCHF5 PCNT PGM5 PTEN PTPN12 SASH1 SNTA1 SNTB1 SNTB2
Entrez ID		5239	7402
HPRD ID		02990	00547
Ensembl ID		ENSG00000154330	ENSG00000152818
Uniprot IDs		Q15124	P46939 Q5T097 Q6LBS5
PDB IDs		7U21	1BHD 1QAG 6M5G
Enriched GO Terms of Interacting Partners?		Vinculin Binding Dystrophin-associated Glycoprotein Complex Filopodium Membrane Regulation Of Sodium Ion Transmembrane Transport Regulation Of Sodium Ion Transport Filopodium Sarcolemma Muscle Organ Development Muscle Structure Development Muscle Contraction Postsynaptic Membrane Muscle System Process Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Regulation Of Metal Ion Transport Synaptic Signaling Actin Binding Syntrophin Complex Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion Regulation Of Monoatomic Ion Transport Cell-substrate Junction Contractile Ring Regulation Of Skeletal Muscle Contraction By Calcium Ion Signaling Dystroglycan Binding Cell-cell Signaling Signaling Nitric-oxide Synthase Binding Cell Communication Costamere Protein-containing Complex Neuron Projection Terminus Regulation Of Skeletal Muscle Contraction Muscle Cell Cellular Homeostasis Peptide Biosynthetic Process Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Synapse Myosin Binding Response To Muscle Stretch Maintenance Of Blood-brain Barrier Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cardiac Muscle Cell Action Potential Structural Constituent Of Muscle Cardiac Muscle Contraction Motile Cilium Assembly Myofibril Peptide Metabolic Process Animal Organ Development Cytoskeleton System Process	Dystrophin-associated Glycoprotein Complex Sarcolemma Cytoskeleton Synapse Focal Adhesion Costamere Filopodium Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Synaptic Signaling PDZ Domain Binding Muscle Contraction Actin Binding Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Syntrophin Complex Cell Projection Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cell Communication Muscle System Process Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Cell-matrix Adhesion Structural Constituent Of Muscle Regulation Of Monoatomic Ion Transmembrane Transport Channel Activator Activity Protein-containing Complex Cell-substrate Junction Sarcomere Regulation Of System Process Regulation Of Metal Ion Transport Positive Regulation Of Cell-matrix Adhesion Dystroglycan Binding Structural Molecule Activity Cell-cell Signaling Cytoplasm Vinculin Binding Nitric-oxide Synthase Binding Calmodulin Binding Signaling Regulation Of Heart Contraction Titin Binding Anchoring Junction Regulation Of Monoatomic Ion Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Regulation Of Cell-substrate Adhesion Cytoskeleton Organization Regulation Of Membrane Potential Nuclear Periphery Muscle Cell Development Plasma Membrane
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