DRAM1 and C1orf21

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		DRAM1	C1orf21
Description		DNA damage regulated autophagy modulator 1	chromosome 1 open reading frame 21
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Lysosomal Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Autophagy Apoptotic Process Regulation Of Autophagy Cellular Response To Oxygen-glucose Deprivation
Pathways
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Bone mineral density (total hip) ( 29883787) Brain morphology (MOSTest) ( 32665545) Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Intracranial aneurysm ( 30823506) Shigella-associated diarrhea ( 33649051) Systemic lupus erythematosus ( 23273568 33272962)	Arterial stiffness index ( 31235810) Chronotype ( 30696823) Medial orbital frontal cortex volume ( 31530798) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		11 interacting genes: APP C1orf21 CD164L2 CLRN1 CREB3 EPS15 EVI2B GPR42 LRRC4C MS4A7 TIMMDC1	1 interacting genes: DRAM1
Entrez ID		55332	81563
HPRD ID		07743	12721
Ensembl ID		ENSG00000136048	ENSG00000116667
Uniprot IDs		Q8N682	Q9H246
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Monocyte Chemotaxis Regulation Of Monocyte Chemotaxis Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Deacetylase Activity Myeloid Cell Development Membrane Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Mononuclear Cell Migration Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Response To Endoplasmic Reticulum Stress Clathrin-coated Pit Positive Regulation Of Leukocyte Chemotaxis Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization	Cellular Response To Oxygen-glucose Deprivation Response To Oxygen-glucose Deprivation
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