CANT1 and CLRN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CANT1	CLRN1
Description		calcium activated nucleotidase 1	clarin 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Membrane Golgi Cisterna Membrane Specific Granule Lumen Extracellular Exosome Tertiary Granule Lumen Ficolin-1-rich Granule Lumen	Plasma Membrane Microvillus Microtubule Cytoskeleton Membrane Lamellipodium Trans-Golgi Network Transport Vesicle Stereocilium Basal Part Of Cell Actin-based Cell Projection
	Molecular Function	GDP Phosphatase Activity Calcium Ion Binding Protein Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Protein Homodimerization Activity ADP Phosphatase Activity UDP Phosphatase Activity Metal Ion Binding	Protein Binding
	Biological Process	Proteoglycan Biosynthetic Process Positive Regulation Of Canonical NF-kappaB Signal Transduction	Actin Filament Organization Visual Perception Sensory Perception Of Sound Positive Regulation Of Lamellipodium Assembly Photoreceptor Cell Maintenance Cell Motility Neuromuscular Process Controlling Balance Sensory Perception Of Light Stimulus Equilibrioception Auditory Receptor Cell Stereocilium Organization Auditory Receptor Cell Development
Pathways		Neutrophil degranulation
Drugs		Phosphomethylphosphonic acid guanosyl ester
Diseases		Desbuquois syndrome	Usher syndrome (US)
GWAS			Childhood asthma exacerbations in long-acting beta2-agonist treatment ( 33706416) Chronotype ( 30696823) Non-alcoholic fatty liver disease activity score in non-alcoholic fatty liver disease ( 31311600)
Interacting Genes		4 interacting genes: CLRN1 FAM209A GOLPH3 GOLPH3L	28 interacting genes: ALG8 BRICD5 C2CD2L CANT1 CCL4L2 CLDN19 CTXN3 DRAM1 FAM24B FUT9 ITGAM MGST3 NRM SEC22B SLC34A3 SLC61A1 TMEM140 TMEM147 TMEM222 TMEM239 TMEM31 TMEM50B TMEM86B TMIE TMPPE TMPRSS4 UNC50 ZDHHC15
Entrez ID		124583	7401
HPRD ID		13003	05905
Ensembl ID		ENSG00000171302	ENSG00000163646
Uniprot IDs		Q8WVQ1	P58418
PDB IDs		1S18 1S1D 2H2N 2H2U
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Budding Cargo Adaptor Activity Protein Targeting To Golgi Apparatus Golgi Cisterna Phosphatidylinositol-4-phosphate Binding Golgi To Plasma Membrane Protein Transport Vesicle Budding From Membrane Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Establishment Of Protein Localization To Plasma Membrane Golgi To Plasma Membrane Transport Golgi Cisterna Membrane Post-Golgi Vesicle-mediated Transport Golgi Organization Vesicle-mediated Transport To The Plasma Membrane Positive Regulation Of Protein Secretion Asymmetric Golgi Ribbon Formation Protein Localization To Plasma Membrane Trans-Golgi Network Cell Adhesion Molecule Production Cellular Response To Rapamycin Protein Targeting Establishment Of Protein Localization To Membrane Protein Retention In Golgi Apparatus Protein Localization To Cell Periphery Equilibrioception Positive Regulation Of Protein Transport Regulation Of Protein Secretion Response To Rapamycin Golgi Vesicle Transport Auditory Receptor Cell Development Actin-based Cell Projection Positive Regulation Of Secretion By Cell Vesicle Organization Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Protein Localization To Membrane Lipid Binding Establishment Of Protein Localization To Organelle Golgi Ribbon Formation Cellular Response To Ether Inner Ear Receptor Cell Development Auditory Receptor Cell Stereocilium Organization Trans-Golgi Network Transport Vesicle Basal Part Of Cell Regulation Of Protein Transport Positive Regulation Of Protein Localization Leukocyte Tethering Or Rolling Response To Ether Localization Within Membrane Regulation Of Establishment Of Protein Localization	Membrane
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