UPK3A and UPK1B

Number of citations of the paper that reports this interaction (PubMedID 12475947)
53

Data Source:
HPRD (in vivo)

		UPK3A	UPK1B
Description		uroplakin 3A	uroplakin 1B
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque	Membrane Apical Plasma Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque
	Molecular Function	Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Cell Morphogenesis Kidney Development Water Transport Urea Transport Epithelial Cell Differentiation Potassium Ion Homeostasis Sodium Ion Homeostasis Urinary Bladder Development	Response To Bacterium Epithelial Cell Differentiation
Pathways
Drugs
Diseases		Renal agenesis and Renal adysplasia
GWAS		Height ( 31562340) Pulmonary function in asthmatics ( 23541324)	Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)
Interacting Genes		3 interacting genes: SGTA SGTB UPK1B	59 interacting genes: BCL2L13 BEST2 BIK BNIP2 CATSPERH CD53 CD69 CD79A CERS4 CLDN7 CYB5R3 DAGLA EDAR ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A1 SLC10A2 SLC16A2 SLC18A1 SLC35H1 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1
Entrez ID		7380	7348
HPRD ID		15625	03853
Ensembl ID		ENSG00000100373	ENSG00000114638
Uniprot IDs		O75631	O75841
PDB IDs
Enriched GO Terms of Interacting Partners?		TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Protein Targeting Molecular Adaptor Activity Apical Plasma Membrane Urothelial Plaque BAT3 Complex Binding Establishment Of Protein Localization To Organelle Negative Regulation Of ERAD Pathway Localization Within Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Protein Heterooligomerization Protein Insertion Into ER Membrane Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Response To Endoplasmic Reticulum Stress Hsp70 Protein Binding	Membrane Protein Binding Plasma Membrane Bile Acid:sodium Symporter Activity
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