UPK1B and UPK3A

Number of citations of the paper that reports this interaction (PubMedID 12475947)
53

Data Source:
HPRD (in vivo)

		UPK1B	UPK3A
Description		uroplakin 1B	uroplakin 3A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Membrane Apical Plasma Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Apical Plasma Membrane Extracellular Exosome Apical Plasma Membrane Urothelial Plaque
	Molecular Function	Structural Molecule Activity Protein Binding	Protein Binding
	Biological Process	Response To Bacterium Epithelial Cell Differentiation	Cell Morphogenesis Kidney Development Water Transport Urea Transport Epithelial Cell Differentiation Potassium Ion Homeostasis Sodium Ion Homeostasis Urinary Bladder Development
Pathways
Drugs
Diseases			Renal agenesis and Renal adysplasia
GWAS		Gemcitabine-induced early high-grade neutropenia in pancreatic cancer ( 30889042)	Height ( 31562340) Pulmonary function in asthmatics ( 23541324)
Interacting Genes		59 interacting genes: BCL2L13 BEST2 BIK BNIP2 CATSPERH CD53 CD69 CD79A CERS4 CLDN7 CYB5R3 DAGLA EDAR ERGIC3 FAM209A FFAR2 FKBP7 FNDC9 GJA8 GJB1 GPR161 GPR37L1 GPX8 ISLR2 ITGB2 KASH5 KCNJ6 KIR2DL3 KLRC1 LMNA MFF MS4A4A NEMP1 PDZK1IP1 PIK3IP1 PLPP4 RHCG SAR1A SDHAF4 SHISA4 SIT1 SLC10A1 SLC10A2 SLC16A2 SLC18A1 SLC35H1 SLC39A2 SPINT1 SSMEM1 STX1A SYT9 TMEM139 TMEM237 TMEM45B TMEM54 TMEM91 TMUB2 UPK3A VSIG1	3 interacting genes: SGTA SGTB UPK1B
Entrez ID		7348	7380
HPRD ID		03853	15625
Ensembl ID		ENSG00000114638	ENSG00000100373
Uniprot IDs		O75841	O75631
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Protein Binding Plasma Membrane Bile Acid:sodium Symporter Activity	TRC Complex Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Establishment Of Protein Localization To Endoplasmic Reticulum Protein Targeting To ER Protein Targeting To Membrane Establishment Of Protein Localization To Membrane Protein Targeting Molecular Adaptor Activity Apical Plasma Membrane Urothelial Plaque BAT3 Complex Binding Establishment Of Protein Localization To Organelle Negative Regulation Of ERAD Pathway Localization Within Membrane Tail-anchored Membrane Protein Insertion Into ER Membrane Positive Regulation Of ERAD Pathway Regulation Of ERAD Pathway Protein Heterooligomerization Protein Insertion Into ER Membrane Positive Regulation Of Response To Endoplasmic Reticulum Stress Negative Regulation Of Response To Endoplasmic Reticulum Stress Hsp70 Protein Binding
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