RPS29 and ADH6

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		RPS29	ADH6
Gene Name		ribosomal protein S29	alcohol dehydrogenase 6 (class V)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Focal Adhesion Small Ribosomal Subunit Cytosolic Small Ribosomal Subunit Extracellular Vesicular Exosome	Cytosol Extracellular Vesicular Exosome
	Molecular Function	Structural Constituent Of Ribosome Zinc Ion Binding	Alcohol Dehydrogenase (NAD) Activity Alcohol Dehydrogenase Activity, Zinc-dependent Zinc Ion Binding Ethanol Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Cellular Protein Metabolic Process	Ethanol Oxidation Xenobiotic Metabolic Process Small Molecule Metabolic Process Response To Ethanol
Pathways		Nonsense-Mediated Decay (NMD) Translation initiation complex formation Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Ribosomal scanning and start codon recognition Formation of the ternary complex, and subsequently, the 43S complex Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)	Defective CYP2R1 causes Rickets vitamin D-dependent 1B (VDDR1B) Defective FMO3 causes Trimethylaminuria (TMAU) Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR) Defective CYP27A1 causes Cerebrotendinous xanthomatosis (CTX) Defective CYP11B1 causes Adrenal hyperplasia 4 (AH4) Defective CYP26B1 causes Radiohumeral fusions with other skeletal and craniofacial anomalies (RHFCA) Ethanol oxidation Metabolic disorders of biological oxidation enzymes Defective CYP1B1 causes Glaucoma Defective CYP27B1 causes Rickets vitamin D-dependent 1A (VDDR1A) Phase 1 - Functionalization of compounds Defective CYP17A1 causes Adrenal hyperplasia 5 (AH5) Defective CYP19A1 causes Aromatase excess syndrome (AEXS) Defective CYP7B1 causes Spastic paraplegia 5A, autosomal recessive (SPG5A) and Congenital bile acid synthesis defect 3 (CBAS3) Defective CYP4F22 causes Ichthyosis, congenital, autosomal recessive 5 (ARCI5) Defective CYP26C1 causes Focal facial dermal dysplasia 4 (FFDD4) Defective CYP24A1 causes Hypercalcemia, infantile (HCAI) Defective CYP2U1 causes Spastic paraplegia 56, autosomal recessive (SPG56) Defective MAOA causes Brunner syndrome (BRUNS) Defective CYP11B2 causes Corticosterone methyloxidase 1 deficiency (CMO-1 deficiency) Defective CYP21A2 causes Adrenal hyperplasia 3 (AH3) Biological oxidations
Drugs
Diseases
GWAS		Post-traumatic stress disorder (asjusted for relatedness) ( 23726511) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738) Visceral fat ( 22589738)	Alcohol dependence ( 23456092) Esophageal cancer ( 19698717) QRS duration ( 23534349)
Protein-Protein Interactions		4 interactors: ADH6 CTBP2 SMARCD1 UMPS	8 interactors: ANKRD17 ARRB1 KRAS RASSF5 RPAIN RPS29 RSL1D1 TNIP1
Entrez ID		6235	130
HPRD ID		04698	00067
Ensembl ID		ENSG00000213741	ENSG00000172955
Uniprot IDs		P62273	E9PBI1 P28332 Q8IUN7
PDB IDs		2ZKQ 3J3A
Enriched GO Terms of Interacting Partners?		'de Novo' UMP Biosynthetic Process Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Chromatin Binding 'de Novo' Pyrimidine Nucleobase Biosynthetic Process Chromatin-mediated Maintenance Of Transcription UMP Biosynthetic Process Ethanol Oxidation Nucleosome Disassembly White Fat Cell Differentiation Positive Regulation Of Gene Expression, Epigenetic Viral Genome Replication Pyrimidine Nucleobase Metabolic Process	Positive Regulation Of Ras Protein Signal Transduction Response To Light Stimulus Positive Regulation Of Small GTPase Mediated Signal Transduction Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Response To Radiation Regulation Of MAPK Cascade Positive Regulation Of Rac Protein Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of ERK1 And ERK2 Cascade Regulation Of Protein Localization Positive Regulation Of Intracellular Signal Transduction Regulation Of Protein Ubiquitination Positive Regulation Of MDA-5 Signaling Pathway Response To Stress Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Smooth Muscle Cell Differentiation Regulation Of I-kappaB Kinase/NF-kappaB Signaling Positive Regulation Of Protein Modification Process Positive Regulation Of RIG-I Signaling Pathway
Tagcloud ?		26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying	aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Difference) ?		26s a2 carcinogenesis consistently cytochromosome detecting differentially dot dysplasia est etc expressions ferritin fragments gastric hybridization hypothetical mucosa oxidase proteasome rps12 screen semi ssh stages subtractive tags transcriptase verifying	aflatoxin areca arecoline bard1 betel brms1 ccnd2 cdk2ap1 cdkn1a cdkn2b chewing exonic fermented fgfr4 flnc gas1 hras il12b il8 indels msh6 nbl1 nitrosamines northeast nut quid rassf1 tobacco toxogenomic
Tagcloud (Intersection) ?