C6 and SART3

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		C6	SART3
Gene Name		complement component 6	squamous cell carcinoma antigen recognized by T cells 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Region Membrane Attack Complex Extracellular Vesicular Exosome	Nucleus Nucleoplasm U6atac SnRNP Cytoplasm Cajal Body Nuclear Speck U4/U6 X U5 Tri-snRNP Complex U4/U6 SnRNP U4atac/U6atac SnRNP
	Molecular Function	Protein Binding	Nucleotide Binding Protein Binding U6 SnRNA Binding U4 SnRNA Binding U6atac SnRNA Binding Histone Binding Poly(A) RNA Binding Ubiquitin-specific Protease Binding
	Biological Process	In Utero Embryonic Development Positive Regulation Of Activation Of Membrane Attack Complex Complement Activation Complement Activation, Classical Pathway Cytolysis Regulation Of Complement Activation Innate Immune Response Positive Regulation Of Angiogenesis	Spliceosomal Tri-snRNP Complex Assembly Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome Cell Morphogenesis Nucleosome Assembly Regulation Of Gene Expression Homeostasis Of Number Of Cells Hematopoietic Stem Cell Proliferation Positive Regulation Of Histone Deubiquitination
Pathways		Regulation of Complement cascade Complement cascade Terminal pathway of complement Innate Immune System
Drugs
Diseases
GWAS		Response to fenofibrate (adiponectin levels) ( 23149075)
Protein-Protein Interactions		4 interactors: C5 F2 MGEA5 SART3	12 interactors: AR C6 COIL HIST2H2AC HIST2H2BE KPNA2 LSM7 MEGF10 PRPF3 RNPS1 USP15 USP4
Entrez ID		729	9733
HPRD ID		01956	11532
Ensembl ID		ENSG00000039537	ENSG00000075856
Uniprot IDs		P13671	B7ZKM0 Q15020
PDB IDs		3T5O 4A5W 4E0S	2DO4
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Cellular Protein Metabolic Process Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Ion Transport Regulation Of Protein Metabolic Process Regulation Of Proteolysis Positive Regulation Of Calcium Ion Transport Positive Regulation Of Transport Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Histone Deubiquitination Positive Regulation Of Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway Negative Regulation Of Protein Metabolic Process Positive Regulation Of Protein Modification Process Regulation Of Ion Homeostasis Protein Activation Cascade Negative Regulation Of Macrophage Chemotaxis Negative Regulation Of Cardiac Muscle Adaptation Regulation Of Cellular Localization Regulation Of Calcium Ion Transport Positive Regulation Of Protein Secretion Positive Regulation Of Ion Transport Positive Regulation Of Metabolic Process Leukocyte Migration Positive Regulation Of Intracellular Transport Protein Deglycosylation Negative Regulation Of Protein Glycosylation Homeostatic Process Negative Regulation Of Dopamine Secretion Cellular Calcium Ion Homeostasis Regulation Of Protein Deubiquitination Calcium Ion Homeostasis Positive Regulation Of Secretion Positive Regulation Of Protein Transport Positive Regulation Of Growth Hormone Secretion DATP Metabolic Process Negative Regulation Of Leukocyte Chemotaxis Negative Regulation Of Norepinephrine Secretion Negative Regulation Of Proteolysis Negative Regulation Of Protein Processing Regulation Of Protein Secretion Positive Regulation Of Chemokine Secretion Regulation Of Growth Hormone Secretion Regulation Of Protein Glycosylation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Fibrinolysis Regulation Of Protein Processing Cellular Metal Ion Homeostasis	RNA Splicing Spliceosomal Tri-snRNP Complex Assembly MRNA Processing MRNA Metabolic Process RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly Cellular Macromolecule Catabolic Process Negative Regulation Of Integrin Biosynthetic Process Skeletal Muscle Satellite Cell Proliferation Skeletal Muscle Cell Proliferation Histone H2B Conserved C-terminal Lysine Deubiquitination Skeletal Muscle Satellite Cell Activation Protein Deubiquitination Protein Modification By Small Protein Removal Positive Regulation Of Integrin Biosynthetic Process Positive Regulation Of Activation Of Membrane Attack Complex Regulation Of Integrin Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Skeletal Muscle Satellite Cell Differentiation RNA Catabolic Process Recognition Of Apoptotic Cell Regulation Of Proteasomal Protein Catabolic Process Monoubiquitinated Protein Deubiquitination Positive Regulation Of Transcription From RNA Polymerase III Promoter Humoral Immune Response Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Nucleocytoplasmic Transport Pathway-restricted SMAD Protein Phosphorylation Nuclear Transport Catabolic Process Positive Regulation Of Humoral Immune Response
Tagcloud ?		appeared confluence confluent conversely culture d differentially exponential glioma half igf ir ka largest late later mannose phase phases phosphate post scatchard seeding showing stage stages statistically stopped values	a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Difference) ?		appeared confluence confluent conversely culture d differentially exponential glioma half igf ir ka largest late later mannose phase phases phosphate post scatchard seeding showing stage stages statistically stopped values	a24 alleles antigen antigens attempted bc cd8 ctls efficiently enhancer epitope ezh2735 hla homolog igg immunotherapy leukocyte mononuclear mrp3 mrp31293 multidrug panel peptides polycomb reactive rejection thereafter zeste
Tagcloud (Intersection) ?