TENT5C and MVP

Number of citations of the paper that reports this interaction (PubMedID 24722188)
69

Data Source:
BioGRID (two hybrid)

		TENT5C	MVP
Description		terminal nucleotidyltransferase 5C	major vault protein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Centrosome Cytoskeleton	Extracellular Region Nucleus Nuclear Pore Cytoplasm Cytosol Cytoskeleton Membrane Secretory Granule Lumen Perinuclear Region Of Cytoplasm Extracellular Exosome Ficolin-1-rich Granule Lumen Ribonucleoprotein Complex
	Molecular Function	RNA Binding Protein Binding Transferase Activity Nucleotidyltransferase Activity Poly(A) RNA Polymerase Activity	Protein Binding Protein Kinase Binding Protein Phosphatase Binding Identical Protein Binding
	Biological Process	In Utero Embryonic Development Negative Regulation Of Cell Differentiation MRNA Stabilization	Cell Population Proliferation Protein Transport Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity Protein Activation Cascade
Pathways			Neutrophil degranulation
Drugs
Diseases
GWAS			Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		7 interacting genes: AP2B1 DAZAP2 MVP PLK4 PRKN RHOXF2 TRIP6	69 interacting genes: ADAMTSL4 BANP C1orf94 CALCOCO2 CAMK2B CKAP4 DISC1 DLX2 DTX2 EPHX2 ESR1 FMR1 FNDC3B FXR1 FXR2 GIT2 GOLGA2 HP HSPA13 IHO1 KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MRTFA MT-CYB NNT NOTCH2NLA NRF1 NTAQ1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF10 RNF111 SAXO1 SERTAD1 SKIL SLC2A4 STN1 TCF4 TENT5C TFCP2 TLE5 TOLLIP TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 TSPOAP1 UBC UBTD2 VAC14 ZBTB32 ZMIZ2
Entrez ID		54855	9961
HPRD ID		13312	05475
Ensembl ID		ENSG00000183508	ENSG00000013364
Uniprot IDs		Q5VWP2	Q14764 X5D2M8 X5D7K9 X5DNU0
PDB IDs		6W36 6W38 6W3I 6W3J 8EQB	1Y7X 9BW5 9BW6 9BW7 9MXH 9MXV
Enriched GO Terms of Interacting Partners?		Synaptic Vesicle Neurotransmitter Transport Clathrin Coat Positive Regulation Of Protein Localization To Membrane Regulation Of Protein Localization To Membrane Cellular Component Assembly Signal Sequence Binding Regulation Of Postsynaptic Membrane Neurotransmitter Receptor Levels Extrinsic Component Of Presynaptic Endocytic Zone Membrane Lewy Body Negative Regulation Of Catalytic Activity Regulation Of Spontaneous Synaptic Transmission Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Protein Catabolic Process At Presynapse Type 2 Mitophagy Negative Regulation Of Intralumenal Vesicle Formation Negative Regulation Of Kinase Activity Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mitochondrial Fission Mitochondrion To Lysosome Vesicle-mediated Transport Regulation Of Endosome Organization Positive Regulation Of Mitochondrial Fusion Mitochondrion-derived Vesicle F-box Domain Binding Kinase Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Hydrogen Sulfide Positive Regulation Of Mitochondrial Membrane Potential Negative Regulation Of Spontaneous Neurotransmitter Secretion Protein Destabilization Response To Curcumin Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake Negative Regulation Of Phosphorylation Cellular Response To L-glutamine Negative Regulation Of Phosphate Metabolic Process Regulation Of Synaptic Vesicle Transport Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Identical Protein Binding Negative Regulation Of Protein Autophosphorylation De Novo Centriole Assembly Involved In Multi-ciliated Epithelial Cell Differentiation De Novo Centriole Assembly Procentriole Replication Complex Procentriole Deuterosome	Identical Protein Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Translation At Presynapse, Modulating Synaptic Transmission Positive Regulation Of Biosynthetic Process Cytoplasm Regulation Of Neurogenesis Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Long-term Neuronal Synaptic Plasticity PML Body Positive Regulation Of RNA Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of Nervous System Development Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleus Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process Translation Regulator Activity Regulation Of Neuronal Synaptic Plasticity TFIIB-class Transcription Factor Binding Viral Penetration Into Host Nucleus Negative Regulation Of Telomere Maintenance Via Telomerase Benzodiazepine Receptor Binding Regulation Of Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II RNA Strand Annealing Activity Regulation Of MiRNA-mediated Gene Silencing Somite Specification Dentate Gyrus Development Single-stranded Telomeric DNA Binding MRNA 3'-UTR Binding Regulation Of Macromolecule Biosynthetic Process Regulation Of Post-transcriptional Gene Silencing Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of DNA Biosynthetic Process Regulation Of Viral Process Protein Binding Non-canonical NF-kappaB Signal Transduction Negative Regulation Of Chromosome Organization Positive Regulation Of Neurogenesis Intracellular Membraneless Organelle Presynapse Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Catabolic Process
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