TPM4 and TCERG1

Number of citations of the paper that reports this interaction (PMID 15456888)
27

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		TPM4	TCERG1
Gene Name		tropomyosin 4	transcription elongation regulator 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Podosome Cytosol Cytoskeleton Muscle Thin Filament Tropomyosin Focal Adhesion Membrane Cortical Cytoskeleton Filamentous Actin Extracellular Vesicular Exosome	Nucleus Nucleolus Actin Cytoskeleton
	Molecular Function	Actin Binding Calcium Ion Binding Structural Constituent Of Muscle	RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Transcription Coactivator Activity Protein Binding Poly(A) RNA Binding Proline-rich Region Binding
	Biological Process	Osteoblast Differentiation Movement Of Cell Or Subcellular Component Muscle Contraction Muscle Filament Sliding	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter
Pathways		Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS		Mean platelet volume ( 22139419 22423221) Platelet counts ( 22139419)
Protein-Protein Interactions		5 interactors: LNX1 PACSIN1 TCERG1 TPM1 TRIP6	52 interactors: ABI1 BARD1 BRD4 CHAF1A CHD3 CPSF6 CYFIP1 CYFIP2 DIAPH1 DIAPH2 DNAJB9 EVL FANCA FANCC FMNL1 GRB2 HNRNPH1 HNRNPK HNRNPM HNRNPU HSPA1A HSPA5 HSPA8 HTT JUNB LUC7L NONO NPM1 NUDT21 PCBP1 PIAS4 POLR2A PSPC1 SETDB1 SF1 SF3A1 SF3A2 SF3A3 SF3B1 SF3B2 SF3B3 SF3B4 SFPQ SRSF1 SUMO1 TPM4 U2AF2 WAS WASF2 WBP4 WIPF2 WWOX
Entrez ID		7171	10915
HPRD ID		11734	10393
Ensembl ID		ENSG00000167460	ENSG00000113649
Uniprot IDs		P67936	O14776
PDB IDs			2DK7 2DOD 2DOE 2DOF 2E71 2KIQ 2KIS 2NNT 3HFH 4FQG
Enriched GO Terms of Interacting Partners?			MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Heterocycle Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Nitrogen Compound Metabolic Process MRNA 3'-splice Site Recognition Cellular Component Assembly MRNA Splice Site Selection Spliceosomal Complex Assembly Regulation Of RNA Splicing Cellular Macromolecular Complex Assembly Ribonucleoprotein Complex Assembly Cellular Metabolic Process Protein Complex Assembly Cellular Process Positive Regulation Of RNA Splicing Cellular Response To Stress Regulation Of MRNA Processing Actin Polymerization Or Depolymerization Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Cellular Response To DNA Damage Stimulus Response To Stress DNA Repair Ribonucleoprotein Complex Biogenesis Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Transcription, DNA-templated Viral Process Phagocytosis Regulation Of Gene Expression Fc Receptor Signaling Pathway RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process MRNA 3'-end Processing Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Metabolic Process Lamellipodium Morphogenesis Rhythmic Process Developmental Process
Tagcloud ?		12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas snrnp25 ssx1 ssx2 syt tpm3 transcriptome	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Difference) ?		12q alk backgroundthe ccnd3 conclusionsour ews fli1 foxo1 fusion fusions harbor inactivating kcnmb4 lrp1 methodstranscriptome opportunities osteosarcoma osteosarcomas pax3 resultsnine sanger saos sarcomas snrnp25 ssx1 ssx2 syt tpm3 transcriptome	12p13 12q21 17q11 3q26 5q22 5q32 acgh bac balanced ccnd2 clonality cnas concordant cryptic cytogenetics emp1 evi1 evolving exploratory hidden imbalances karyotypically karyotyping kitlg nf1 platforms recurring submicroscopic unidentified
Tagcloud (Intersection) ?