TPD52L2 and TPD52L1

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology)
HPRD (two hybrid)

		TPD52L2	TPD52L1
Description		TPD52 like 2	TPD52 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity	Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Carbohydrate Metabolic Process Regulation Of Cell Population Proliferation	G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of MAP Kinase Activity Positive Regulation Of JNK Cascade Positive Regulation Of Apoptotic Signaling Pathway
Pathways			Golgi Associated Vesicle Biogenesis
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Prostate cancer ( 23535732)	Heel bone mineral density x serum urate levels interaction ( 34046847) Night sleep phenotypes ( 27126917)
Interacting Genes		10 interacting genes: ABHD5 ADORA2B APP CDC42 COQ8A MAL2 SH3GLB1 TPD52 TPD52L1 TPD52L3	15 interacting genes: ABL2 DAPK1 EIF3J GPR135 HDAC1 MAL2 MAP3K5 PAK6 PBX3 TPD52 TPD52L2 TPD52L3 YAE1 YWHAB YWHAZ
Entrez ID		7165	7164
HPRD ID		11947	07236
Ensembl ID		ENSG00000101150	ENSG00000111907
Uniprot IDs		A0A087WYR3 A0A087WZ51 O43399 Q68E05 Q6FGS1	E9PPQ1 J3KNE7 Q16890
PDB IDs
Enriched GO Terms of Interacting Partners?		Lysophosphatidic Acid Acyltransferase Activity Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Phosphatidic Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Protein Localization To Vacuolar Membrane Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Chemokine Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Cytokinesis GBD Domain Binding Storage Vacuole Negative Regulation Of Triglyceride Storage Lipase Activator Activity Positive Regulation Of Membrane Tubulation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Chronic Inflammatory Response G Protein-coupled Adenosine Receptor Activity Relaxation Of Vascular Associated Smooth Muscle Regulation Of Vesicle-mediated Transport Regulation Of Interleukin-6 Production Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of MAPK Cascade	Phosphoserine Residue Binding Cytoplasm Protein Kinase Activity Cellular Response To Oxidative Stress DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Protein Domain Specific Binding Cellular Response To Starvation Response To Starvation Posterior Compartment Specification Anterior Compartment Pattern Formation Negative Regulation Of Protein Localization To Nucleus Protein Sequestering Activity
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