TPD52L2 and COQ8A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TPD52L2	COQ8A
Description		TPD52 like 2	coenzyme Q8A
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Perinuclear Region Of Cytoplasm	Mitochondrion Membrane Extrinsic Component Of Mitochondrial Inner Membrane Mitochondrial Membrane
	Molecular Function	RNA Binding Protein Binding Protein Homodimerization Activity	Nucleotide Binding Protein Kinase Activity Protein Binding ATP Binding Enzyme Activator Activity Kinase Activity Transferase Activity ADP Binding
	Biological Process	Carbohydrate Metabolic Process Regulation Of Cell Population Proliferation	Protein Phosphorylation Ubiquinone Biosynthetic Process Phosphorylation
Pathways			Ubiquinol biosynthesis
Drugs		Phenethyl Isothiocyanate	Fostamatinib
Diseases			Spinocerebellar ataxia (SCA); Machado-Joseph disease (SCA3) Coenzyme Q10 deficiency
GWAS		Prostate cancer ( 23535732)
Interacting Genes		10 interacting genes: ABHD5 ADORA2B APP CDC42 COQ8A MAL2 SH3GLB1 TPD52 TPD52L1 TPD52L3	27 interacting genes: ABHD5 AGTRAP CCDC34 CMTM4 CMTM5 CMTM6 COQ9 DESI2 DTX2 JOSD2 LDAF1 MAL2 MRM1 MTIF3 ORMDL3 PBX3 RABAC1 REEP6 RPRM SH3GLB1 SMPD2 STX10 TFIP11 TMCO2 TMEM239 TPD52L2 UBC
Entrez ID		7165	56997
HPRD ID		11947	07375
Ensembl ID		ENSG00000101150	ENSG00000163050
Uniprot IDs		A0A087WYR3 A0A087WZ51 O43399 Q68E05 Q6FGS1	Q8NI60
PDB IDs			4PED 5I35 7UDP 7UDQ
Enriched GO Terms of Interacting Partners?		Lysophosphatidic Acid Acyltransferase Activity Positive Regulation Of Chronic Inflammatory Response To Non-antigenic Stimulus Amyloid-beta Complex Growth Cone Lamellipodium Neuron Projection Organization Regulation Of Response To Calcium Ion Perinuclear Region Of Cytoplasm Amylin Binding Positive Regulation Of Toll Signaling Pathway Protein Homodimerization Activity Phosphatidic Acid Metabolic Process Phosphatidic Acid Biosynthetic Process Protein Localization To Vacuolar Membrane Regulation Of Chemokine Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Chemokine Production Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of JNK Cascade Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Endothelin Receptor Signaling Pathway Involved In Heart Process Regulation Of Cytokinesis GBD Domain Binding Storage Vacuole Negative Regulation Of Triglyceride Storage Lipase Activator Activity Positive Regulation Of Membrane Tubulation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Chronic Inflammatory Response G Protein-coupled Adenosine Receptor Activity Relaxation Of Vascular Associated Smooth Muscle Regulation Of Vesicle-mediated Transport Regulation Of Interleukin-6 Production Regulation Of Spontaneous Synaptic Transmission Positive Regulation Of Catabolic Process Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of JNK Cascade Axon Midline Choice Point Recognition Positive Regulation Of MAPK Cascade
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