TFE3 and TFEC

Number of citations of the paper that reports this interaction (PMID 8336698)
16

Data Source:
HPRD (in vitro)

		TFE3	TFEC
Gene Name		transcription factor binding to IGHM enhancer 3	transcription factor EC
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm	Nucleoplasm Cytoplasm
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding Protein Dimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Transcription Corepressor Activity Protein Dimerization Activity
	Biological Process	Transcription, DNA-templated Humoral Immune Response Regulation Of Osteoclast Differentiation Positive Regulation Of Cell Adhesion Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To Heat Negative Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		9 interactors: E2F3 HMGB1 MITF SMAD3 SMAD4 SMARCE1 TFEB TFEC YWHAG	8 interactors: DCK DEFB127 HNRNPA1 MITF NAPB TFE3 TFEB ZMAT2
Entrez ID		7030	22797
HPRD ID		02439	05294
Ensembl ID		ENSG00000068323	ENSG00000105967
Uniprot IDs		B4DIA5 P19532 Q5JU74	O14948
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process SMAD Protein Complex Assembly Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transforming Growth Factor Beta2 Production Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Regulation Of Metabolic Process Transcription, DNA-templated Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Gene Expression RNA Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Intracellular Transport Regulation Of Binding Positive Regulation Of Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Transcription From RNA Polymerase II Promoter System Development Positive Regulation Of Stem Cell Differentiation SMAD Protein Signal Transduction Regulation Of Epithelial To Mesenchymal Transition Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Somitogenesis Anatomical Structure Development Endoderm Development Positive Regulation Of Transforming Growth Factor Beta3 Production Negative Regulation Of Apoptotic Cell Clearance Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Embryonic Pattern Specification Cellular Nitrogen Compound Metabolic Process Regulation Of Intracellular Transport	Regulation Of Osteoclast Differentiation Regulation Of Myeloid Leukocyte Differentiation Regulation Of Myeloid Cell Differentiation SNARE Complex Disassembly Humoral Immune Response Immune System Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Canonical Wnt Signaling Pathway Involved In Negative Regulation Of Apoptotic Process Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Deoxyribonucleoside Monophosphate Biosynthetic Process Nucleobase-containing Compound Metabolic Process Immune Response Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Purine-containing Compound Salvage Positive Regulation Of Gene Expression RNA Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Nitrogen Compound Metabolic Process
Tagcloud ?		aas adopt amphipathic bhlh caf cbp cbp2 cofactor confirming e1a fos fused genesis helical helix immunoprecipitate leucine lz melanocyte melanocytes mi microphthalmia myod parallels pigment potentiated resides vp16 zipper	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance fos hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Difference) ?		aas adopt amphipathic bhlh caf cbp cbp2 cofactor confirming e1a fused genesis helical helix immunoprecipitate leucine lz melanocyte melanocytes mi microphthalmia myod parallels pigment potentiated resides vp16 zipper	advantage agonists augment autonomous believed competitive confer conservation define determinants engineered enhance hsc hscs intrinsically klf10 majority namely niches osteoclastogenesis prdm16 renewal robust screen spi1 supports surprisingly unexpectedly
Tagcloud (Intersection) ?		fos