MLX and SAP30BP

Number of citations of the paper that reports this interaction (PubMedID 18255255)
0

Data Source:
BioGRID (two hybrid)

		MLX	SAP30BP
Description		MAX dimerization protein MLX	SAP30 binding protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nucleus Nucleoplasm Intermediate Filament Cytoskeleton
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II	Regulation Of DNA-templated Transcription Response To Virus
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression	NoRC negatively regulates rRNA expression
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 29632382 30297969 30718926) Type 2 diabetes (time to event) ( 32589924) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Rotator cuff tears ( 26350878)
Interacting Genes		31 interacting genes: APP BACH2 BEND7 CASK CCT6A DDIT4L GABARAPL1 GABARAPL2 ID3 KRTAP13-3 LNX1 LNX2 MAD1L1 MEI4 MEOX1 MEOX2 MLXIP MLXIPL MNT MXD1 MXD4 PIAS2 RBM39 RHBDD2 SAP30BP TEPSIN TLE5 TNNT2 UBE2I ZBTB32 ZNF620	25 interacting genes: DHX8 FHL2 FHL3 FRA10AC1 GOLGA2 GSK3B MLX OGT PRKAR1B PUF60 RBM17 RBM39 RPS6KA6 SAP30 SNCA SUPT5H TFIP11 THAP1 THOC1 U2AF2 USP7 WDR77 WDR83 ZNF212 ZNF408
Entrez ID		6945	29115
HPRD ID		04278	17094
Ensembl ID		ENSG00000108788	ENSG00000161526
Uniprot IDs		Q9UH92	Q9UHR5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription By RNA Polymerase II Protein Dimerization Activity Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of RNA Metabolic Process Regulation Of Primary Metabolic Process DNA Binding Somite Specification RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Cellular Response To Nitrogen Starvation Regulation Of Macromolecule Metabolic Process Phosphatidylethanolamine Binding Regulation Of Gene Expression Segment Specification Somite Development GABA Receptor Binding Positive Regulation Of ATP-dependent Activity SUMO Transferase Activity Regulation Of Metabolic Process Positive Regulation Of Glycolytic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Leptomycin B Leptomycin B Binding Regulation Of ATP-dependent Activity SUMO Conjugating Enzyme Activity MAD1 Complex Carbohydrate Response Element Binding Primary Adaptive Immune Response Involving T Cells And B Cells Coated Vesicle Membrane Positive Regulation Of ATP Metabolic Process Negative Regulation Of Metabolic Process	RNA Splicing MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing, Via Transesterification Reactions Nucleus MRNA Metabolic Process Nucleoplasm RNA Metabolic Process RNA Processing Spliceosomal Complex Regulation Of Nucleobase-containing Compound Metabolic Process TOR Signaling Nucleic Acid Metabolic Process Regulation Of RNA Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Protein Catabolic Process Macromolecule Metabolic Process Negative Regulation Of Protein-containing Complex Assembly Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of MRNA Processing Regulation Of Primary Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process TORC1 Signaling Nucleic Acid Binding Regulation Of RNA Splicing Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Catabolic Process Regulation Of Autophagy Negative Regulation Of Proteolysis Involved In Protein Catabolic Process Protein Kinase A Catalytic Subunit Binding Catalytic Step 2 Spliceosome Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Calcium-mediated Signaling Negative Regulation Of Macromolecule Metabolic Process Sin3-type Complex Negative Regulation Of Autophagy Identical Protein Binding Negative Regulation Of Signal Transduction Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Stem Cell Population Maintenance Alternative MRNA Splicing, Via Spliceosome
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