TBCE and TBCD

Number of citations of the paper that reports this interaction (PMID 9265649)
40

Data Source:
HPRD (in vitro)

		TBCE	TBCD
Gene Name		tubulin folding cofactor E	tubulin folding cofactor D
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule	Cytoplasm Microtubule Adherens Junction Tight Junction Lateral Plasma Membrane
	Molecular Function	Chaperone Binding	GTPase Activator Activity Protein Binding Beta-tubulin Binding Chaperone Binding
	Biological Process	Microtubule Cytoskeleton Organization Protein Folding Post-chaperonin Tubulin Folding Pathway Adult Locomotory Behavior Post-embryonic Development Muscle Atrophy Cellular Protein Metabolic Process Developmental Growth Peripheral Nervous System Neuron Axonogenesis 'de Novo' Posttranslational Protein Folding	Protein Folding Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Microtubule Polymerization Adherens Junction Assembly Positive Regulation Of GTPase Activity Cellular Protein Metabolic Process 'de Novo' Posttranslational Protein Folding Transmembrane Transport Tight Junction Assembly
Pathways		Protein folding Post-chaperonin tubulin folding pathway	Protein folding Post-chaperonin tubulin folding pathway Orphan transporters
Drugs
Diseases
GWAS		Adiposity ( 19557161)
Protein-Protein Interactions		2 interactors: TBCD TUBA4A	11 interactors: ACD APP ARL2 DEXI POLR2I POT1 SMAD9 TBCE TERF1 TUBB XRCC6
Entrez ID		6905	6904
HPRD ID		05381	05227
Ensembl ID		ENSG00000116957	ENSG00000141556
Uniprot IDs		B7Z3P1 Q15813	J3KR97 Q9BTW9
PDB IDs
Enriched GO Terms of Interacting Partners?		'de Novo' Posttranslational Protein Folding 'de Novo' Protein Folding Protein Folding Post-chaperonin Tubulin Folding Pathway Negative Regulation Of Microtubule Polymerization Regulation Of Microtubule Polymerization Cellular Response To Interleukin-4 Adherens Junction Assembly Tight Junction Assembly Negative Regulation Of Microtubule Polymerization Or Depolymerization Response To Interleukin-4 Negative Regulation Of Cell-substrate Adhesion Platelet Degranulation Regulation Of Microtubule Polymerization Or Depolymerization Apical Junction Assembly Cellular Component Assembly Negative Regulation Of Protein Polymerization Adherens Junction Organization Protein Polymerization Cell-cell Junction Assembly G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Protein Complex Assembly Regulation Of Microtubule Cytoskeleton Organization Negative Regulation Of Cytoskeleton Organization Regulation Of Microtubule-based Process	Negative Regulation Of Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Telomere Maintenance Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Regulation Of DNA Biosynthetic Process Negative Regulation Of DNA Replication Telomere Assembly Telomere Capping Positive Regulation Of Telomerase Activity Negative Regulation Of Chromosome Organization Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of DNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Microtubule Polymerization Positive Regulation Of Cellular Biosynthetic Process Regulation Of DNA Replication Positive Regulation Of DNA Biosynthetic Process DNA Metabolic Process RNA-dependent DNA Replication Cellular Component Assembly Negative Regulation Of DNA Biosynthetic Process Organelle Organization Regulation Of Microtubule Polymerization Regulation Of Chromosome Organization Telomere Maintenance Via Telomere Lengthening Homeostatic Process Microtubule-based Process Negative Regulation Of Catalytic Activity Positive Regulation Of Cellular Metabolic Process Positive Regulation Of DNA Replication Regulation Of Organelle Organization Regulation Of Microtubule Polymerization Or Depolymerization Positive Regulation Of Single-stranded Telomeric DNA Binding Positive Regulation Of DNA Strand Elongation Maintenance Of Transcriptional Fidelity During DNA-templated Transcription Elongation From RNA Polymerase II Promoter DNA Duplex Unwinding Response To Stimulus DNA Geometric Change Positive Regulation Of Organelle Organization Chromosome Organization Nucleobase-containing Compound Metabolic Process Microtubule Cytoskeleton Organization Synaptic Growth At Neuromuscular Junction Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process
Tagcloud ?		axonal counterpart densities depolymerizing destabilizes deterioration disorganization disrupting fatal filaments gan giant gigaxonin ifs lymphoblast map1b map8 massive microtubule microtubules moderately neuropathy ovoid permitting tbcb tubulin unidentified unstable vimentin	behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel
Tagcloud (Difference) ?		axonal counterpart densities depolymerizing destabilizes deterioration disorganization disrupting fatal filaments gan giant gigaxonin ifs lymphoblast map1b map8 massive microtubule microtubules moderately neuropathy ovoid permitting tbcb tubulin unidentified unstable vimentin	behnke biomicroscopic bucklers corneal dilated dystrophies dystrophy families fundus gcd1 gcd2 granular inheritance inspection korean l527r lattice lcd opacities ophthalmologic p527r p542r r124c r124h r555q refractive reis tgfbi thiel
Tagcloud (Intersection) ?