TAPBP and COPG1

Number of citations of the paper that reports this interaction (PMID 11884415)
13

Data Source:
HPRD (in vivo)

		TAPBP	COPG1
Gene Name		TAP binding protein (tapasin)	coatomer protein complex, subunit gamma 1
Image
Gene Ontology Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane MHC Class I Peptide Loading Complex TAP Complex Integral Component Of Lumenal Side Of Endoplasmic Reticulum Membrane	Golgi Membrane Cytosol COPI Vesicle Coat
	Molecular Function	Protein Binding Peptide Antigen-transporting ATPase Activity MHC Class I Protein Binding Peptide Antigen Binding TAP1 Binding TAP2 Binding Unfolded Protein Binding	Structural Molecule Activity Protein Binding
	Biological Process	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Protein Complex Assembly Retrograde Vesicle-mediated Transport, Golgi To ER Immune Response Peptide Transport Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Amide Transport Peptide Antigen Stabilization	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER COPI Coating Of Golgi Vesicle Establishment Of Golgi Localization Membrane Organization Organelle Transport Along Microtubule
Pathways		Class I MHC mediated antigen processing & presentation Antigen Presentation: Folding, assembly and peptide loading of class I MHC Antigen processing-Cross presentation ER-Phagosome pathway Adaptive Immune System	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs			S-(Dimethylarsenic)Cysteine
Diseases
GWAS
Protein-Protein Interactions		8 interactors: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2	15 interactors: ARCN1 ARF1 COPB1 COPE COPG2 COPZ1 COPZ2 DRD1 H2AFX PPBP PTGES3 RHOQ SACM1L TAPBP TMED10
Entrez ID		6892	22820
HPRD ID		09061	09887
Ensembl ID		ENSG00000231925	ENSG00000181789
Uniprot IDs		O15533	Q9Y678
PDB IDs		3F8U	1R4X
Enriched GO Terms of Interacting Partners?		Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-dependent Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Intracellular Protein Transport Cytosol To ER Transport Retrograde Vesicle-mediated Transport, Golgi To ER Viral Process Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent Intracellular Transport Of Viral Protein In Host Cell Cellular Protein Localization Protein Transport Establishment Of Protein Localization Intracellular Transport COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Protein Localization Establishment Of Localization In Cell Golgi Vesicle Budding Cellular Localization Intracellular Transport Of Virus Vesicle Targeting, To, From Or Within Golgi Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class I, TAP-independent Golgi Vesicle Transport Localization Within Membrane Vesicle Targeting Positive Regulation Of Immune System Process Intra-Golgi Vesicle-mediated Transport Positive Regulation Of T Cell Mediated Cytotoxicity Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Leukocyte Mediated Cytotoxicity Immune System Process Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Regulation Of Leukocyte Mediated Cytotoxicity Membrane Budding Type I Interferon Signaling Pathway Cellular Response To Type I Interferon Peptide Antigen Assembly With MHC Class I Protein Complex Response To Type I Interferon Peptide Transport Interferon-gamma-mediated Signaling Pathway Regulation Of Immune System Process Interaction With Host Positive Regulation Of Memory T Cell Activation Positive Regulation Of Adaptive Immune Response Cellular Response To Interferon-gamma	Retrograde Vesicle-mediated Transport, Golgi To ER COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Golgi Vesicle Transport Membrane Budding Vesicle-mediated Transport Establishment Of Localization In Cell Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Intracellular Transport Cellular Localization Establishment Of Organelle Localization Protein Transport Intra-Golgi Vesicle-mediated Transport Establishment Of Protein Localization Organelle Localization Protein Localization Intracellular Protein Transport Cellular Protein Localization Membrane Organization Transport Organelle Organization Long Term Synaptic Depression Cerebellar Purkinje Cell Layer Maturation Peptide Antigen Stabilization Negative Regulation Of Synaptic Transmission Glucose Transport Hexose Transport Sensitization ER To Golgi Vesicle-mediated Transport Habituation Cerebellum Maturation Adult Locomotory Behavior Phosphatidylinositol Biosynthetic Process Carbohydrate Transport Nonassociative Learning Chaperone Cofactor-dependent Protein Refolding Response To Alkaloid Operant Conditioning Conditioned Taste Aversion Positive Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Regulation Of Adenylate Cyclase Activity Involved In G-protein Coupled Receptor Signaling Pathway Lipid Biosynthetic Process Adult Behavior Regulation Of Synaptic Plasticity
Tagcloud ?		african c3ar1 chabaudi cope demonstration falciparum fcgr3b highlighted hosts implicate implicating interplay lrrc25 malaria mapped mounted noncoding plasmodium polygenic rad21 responders retn sco1 signature slc39a8 slc3a2 transcriptomes validated west
Tagcloud (Difference) ?		african c3ar1 chabaudi cope demonstration falciparum fcgr3b highlighted hosts implicate implicating interplay lrrc25 malaria mapped mounted noncoding plasmodium polygenic rad21 responders retn sco1 signature slc39a8 slc3a2 transcriptomes validated west
Tagcloud (Intersection) ?