TAPBP and COPG2

Number of citations of the paper that reports this interaction (PubMedID 11884415)
0

Data Source:
HPRD (in vivo)

		TAPBP	COPG2
Description		TAP binding protein	coat protein complex I subunit gamma 2
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Phagocytic Vesicle Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane MHC Class I Peptide Loading Complex Tapasin-ERp57 Complex Lumenal Side Of Endoplasmic Reticulum Membrane	Golgi Membrane Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Bounding Membrane Of Organelle
	Molecular Function	Protein Binding MHC Class I Protein Complex Binding MHC Class I Protein Binding Peptide Antigen Binding Protein Folding Chaperone TAP1 Binding TAP2 Binding Unfolded Protein Binding Molecular Adaptor Activity TAP Complex Binding	Structural Molecule Activity
	Biological Process	MHC Class Ib Protein Complex Assembly Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Assembly With MHC Class I Protein Complex Protein Folding Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Regulation Of Gene Expression Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Peptide Antigen Stabilization Regulation Of Protein Complex Stability Protein-containing Complex Assembly	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Protein Secretion Protein Transport Vesicle-mediated Transport Organelle Transport Along Microtubule
Pathways		ER-Phagosome pathway Antigen Presentation: Folding, assembly and peptide loading of class I MHC	COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases		Bare lymphocyte syndrome (BLS) type1
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576)	A body shape index ( 34021172) Pancreatic cancer ( 25086665) Waist circumference adjusted for body mass index ( 34021172) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		9 interacting genes: CALR COPB1 COPG1 COPG2 HLA-A HLA-C TAP1 TAP2 UBC	12 interacting genes: ARCN1 ARL1 COPB1 COPE COPG1 COPZ1 COPZ2 DRD1 HES4 PTGES3 TAPBP TMED10
Entrez ID		6892	26958
HPRD ID		09061	05074
Ensembl ID		ENSG00000231925	ENSG00000158623
Uniprot IDs		A0A024RCT1 A0A0A0MSV9 A0A0A0MT98 A0A8V8TQC5 O15533	A0A140VK12 Q9UBF2
PDB IDs		3F8U 6ENY 7QNG 7QPD 7TUE 7TUF 7TUG
Enriched GO Terms of Interacting Partners?		MHC Class I Peptide Loading Complex Peptide Antigen Assembly With MHC Class I Protein Complex Endoplasmic Reticulum Membrane Phagocytic Vesicle Membrane Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Antigen Processing And Presentation Of Endogenous Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Peptide Antigen Binding Antigen Processing And Presentation Of Peptide Antigen COPI Vesicle Coat Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class Ib COPI-coated Vesicle Membrane Antigen Processing And Presentation Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-dependent Peptide Transmembrane Transporter Activity ABC-type Peptide Antigen Transporter Activity TAP Complex Membrane Coat Lumenal Side Of Endoplasmic Reticulum Membrane Positive Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Positive Regulation Of Lymphocyte Mediated Immunity Positive Regulation Of Adaptive Immune Response Intra-Golgi Vesicle-mediated Transport Positive Regulation Of T Cell Mediated Cytotoxicity TAP Binding ABC-type Peptide Transporter Activity TAP1 Binding Regulation Of T Cell Mediated Cytotoxicity Cytosol To Endoplasmic Reticulum Transport Regulation Of Lymphocyte Mediated Immunity Endoplasmic Reticulum Cellular Localization Regulation Of Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains MHC Class Ib Protein Binding Regulation Of Adaptive Immune Response Positive Regulation Of Leukocyte Mediated Cytotoxicity MHC Protein Binding Positive Regulation Of Cell Killing Positive Regulation Of T Cell Mediated Immunity Protein Transport Intracellular Protein Localization MHC Class I Protein Complex Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Positive Regulation Of Immune Effector Process Golgi Membrane Intracellular Transport Adaptive Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Antigen Processing And Presentation Of Endogenous Peptide Antigen Via MHC Class I Via ER Pathway, TAP-independent	COPI Vesicle Coat COPI-coated Vesicle Membrane Transport Vesicle Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Golgi Vesicle Transport Intra-Golgi Vesicle-mediated Transport Golgi Membrane COPI-coated Vesicle Intracellular Protein Transport Endoplasmic Reticulum Membrane Protein Transport Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Intracellular Protein Localization Cytoplasmic Vesicle Golgi Apparatus Membrane Coat Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Localization Protein Localization To Golgi Apparatus Structural Molecule Activity Cis-Golgi Network MHC Class Ib Protein Complex Assembly Peptide Antigen Stabilization Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Cerebellar Purkinje Cell Layer Maturation Phospholipase D Activator Activity Dopamine Neurotransmitter Receptor Activity, Coupled Via Gs G Protein-coupled Receptor Complex Tapasin-ERp57 Complex Adult Locomotory Behavior Secretory Granule Membrane Conditioned Taste Aversion Sensitization TAP2 Binding TAP Complex Binding Prostaglandin-E Synthase Activity Endoplasmic Reticulum Membrane Habituation Operant Conditioning Unfolded Protein Binding TAP1 Binding
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