TAF12 and TAF5

Number of citations of the paper that reports this interaction (PubMedID 9045704)
0

Data Source:
HPRD (in vitro, in vivo)

		TAF12	TAF5
Description		TATA-box binding protein associated factor 12	TATA-box binding protein associated factor 5
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFTC Complex	Chromatin Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity DNA-binding Transcription Factor Binding	Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Identical Protein Binding
	Biological Process	Regulation Of DNA Repair DNA-templated Transcription Initiation Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II	Regulation Of DNA Repair DNA-templated Transcription Initiation Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II Positive Regulation Of DNA-templated Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)	Autism spectrum disorder or schizophrenia ( 28540026) Height ( 31562340) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Schizophrenia ( 23974872 25056061)
Interacting Genes		23 interacting genes: ATF7 CLIC6 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	16 interacting genes: CPSF1 GTF2F2 H3-4 TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6883	6877
HPRD ID		15981	11876
Ensembl ID		ENSG00000120656	ENSG00000148835
Uniprot IDs		A0A804HLG9 Q16514	Q15542
PDB IDs		1H3O 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGI 7EGJ 7ENA 7ENC 7KTR 7KTS 8GXQ 8GXS 8H7G 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS	2NXP 6F3T 6MZC 6MZD 6MZL 6MZM 7EDX 7EG7 7EG8 7EG9 7EGA 7EGB 7EGC 7EGD 7EGE 7EGF 7EGG 7EGI 7EGJ 7ENA 7ENC 8GXQ 8GXS 8WAK 8WAL 8WAN 8WAO 8WAP 8WAQ 8WAR 8WAS
Enriched GO Terms of Interacting Partners?		Transcription Factor TFIID Complex Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II General Transcription Initiation Factor Activity Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Regulation Of DNA-templated Transcription Initiation MRNA Transcription Transcription Preinitiation Complex Assembly DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter Transcription By RNA Polymerase II Protein-DNA Complex Assembly DNA-templated Transcription Transcription Factor TFTC Complex Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm MRNA Metabolic Process Protein Heterodimerization Activity RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein-containing Complex Organization MLL1 Complex Regulation Of DNA Repair Regulation Of RNA Metabolic Process Transcription Cis-regulatory Region Binding Positive Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process DNA Binding Positive Regulation Of Metabolic Process Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress CCAAT-binding Factor Complex Protein-containing Complex Assembly Nucleus Nucleobase-containing Compound Metabolic Process Aryl Hydrocarbon Receptor Binding Regulation Of Gene Expression	RNA Polymerase II General Transcription Initiation Factor Activity Transcription Factor TFIID Complex DNA-templated Transcription Initiation Transcription Initiation At RNA Polymerase II Promoter MRNA Transcription By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly MRNA Transcription Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Protein-DNA Complex Assembly Transcription By RNA Polymerase II Transcription Factor TFTC Complex DNA-templated Transcription MRNA Metabolic Process Nucleobase-containing Compound Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Protein Heterodimerization Activity Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Protein-containing Complex Assembly Nucleoplasm MLL1 Complex Positive Regulation Of RNA Metabolic Process Protein-containing Complex Organization Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleic Acid Metabolic Process Regulation Of DNA Repair Cellular Component Assembly Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II SAGA Complex Positive Regulation Of Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Aryl Hydrocarbon Receptor Binding Regulation Of Nucleobase-containing Compound Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleus Male Germ Cell Nucleus Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Positive Regulation Of Metabolic Process
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