TAF5 and TAF4

Number of citations of the paper that reports this interaction (PMID 14580349)
15

Data Source:
HPRD (in vivo, in vitro)

		TAF5	TAF4
Gene Name		TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa	TAF4 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 135kDa
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Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor TFIID Complex Nucleolus Actin Cytoskeleton Transcription Factor TFTC Complex Intracellular Membrane-bounded Organelle	Nucleoplasm Transcription Factor TFIID Complex Cytoplasm Transcription Factor TFTC Complex MLL1 Complex
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Histone Acetyltransferase Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Dimerization Activity	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Protein Heterodimerization Activity
	Biological Process	DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Chromatin Modification Histone Acetylation	Ovarian Follicle Development DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Gene Expression Viral Process Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome	RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription HIV Infection RNA Polymerase II Pre-transcription Events Late Phase of HIV Life Cycle HIV Life Cycle HIV Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase II HIV Promoter Escape RNA Polymerase II Transcription Initiation Transcription of the HIV genome
Drugs
Diseases
GWAS
Protein-Protein Interactions		18 interactors: CPSF1 GTF2F2 HIST3H3 MYC TAF1 TAF10 TAF11 TAF12 TAF15 TAF2 TAF4 TAF6 TAF7 TAF8 TAF9 TAF9B TBP UBE2I	22 interactors: AHR ATF7 CBX3 CBX5 CREM GTF2A1 GTF2A2 HIST3H3 HTT JUN SP1 TAF1 TAF10 TAF11 TAF12 TAF2 TAF5 TAF6 TAF7 TAF8 TAF9 TCF12
Entrez ID		6877	6874
HPRD ID		11876	11797
Ensembl ID		ENSG00000148835	ENSG00000130699
Uniprot IDs		Q15542	O00268
PDB IDs		2NXP	1H3O 2P6V
Enriched GO Terms of Interacting Partners?		Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Viral Process Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Macromolecule Biosynthetic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Histone Acetylation Peptidyl-lysine Modification Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Histone H3 Acetylation Protein Acetylation Positive Regulation Of Transcription, DNA-templated Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Metabolic Process Chromatin Modification Chromosome Organization Histone Modification Chromatin Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Peptidyl-amino Acid Modification Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Response To DNA Damage Stimulus Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator	Transcription Elongation From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation DNA-templated Transcription, Initiation Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Viral Process RNA Metabolic Process Heterocycle Metabolic Process Regulation Of Gene Expression Gene Expression Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Nitrogen Compound Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Histone Acetylation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Positive Regulation By Host Of Viral Transcription Internal Protein Amino Acid Acetylation Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Rhythmic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process RNA Polymerase II Transcriptional Preinitiation Complex Assembly Peptidyl-lysine Modification Interaction With Symbiont Regulation Of Cellular Process Histone H3 Acetylation Positive Regulation Of Viral Transcription Chromatin Modification Circadian Rhythm Chromosome Organization
Tagcloud ?		adjacent amide axillary bre cancerous dss faah ggh glutamyl hazards hydrolase invasive kaplan meier pcaf pir pirin positively predicts pronouncedly qrt rfs signatures taf5l tumoral undifferentiated unfavorable verify warranting	adjacent characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid
Tagcloud (Difference) ?		amide axillary bre cancerous dss faah ggh glutamyl hazards hydrolase invasive kaplan meier pcaf pir pirin positively predicts pronouncedly qrt rfs signatures taf5l tumoral undifferentiated unfavorable verify warranting	characterised directed directing elements embryonic hepatocyte heterodimer highlighting hnf4a inactivation instructive interacts maintain maturation mutually natal occupancy pausing pic post promotes proximal start subset taf12 tafs tfiid
Tagcloud (Intersection) ?		adjacent