SYT5 and SYT3

Number of citations of the paper that reports this interaction (PMID 10531343)
35

Data Source:
HPRD (in vitro, in vivo)

		SYT5	SYT3
Gene Name		synaptotagmin V	synaptotagmin III
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane Dense Core Granule Neuron Projection Neuronal Cell Body Perinuclear Region Of Cytoplasm Recycling Endosome Membrane	Endosome Integral Component Of Membrane Cell Junction Synaptic Vesicle Membrane
	Molecular Function	Transporter Activity Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Metal Ion Binding Protein Heterodimerization Activity	Phosphatidylserine Binding Transporter Activity Calcium-dependent Phospholipid Binding Syntaxin Binding Clathrin Binding Metal Ion Binding
	Biological Process	Energy Reserve Metabolic Process Synaptic Transmission Calcium Ion-dependent Exocytosis Small Molecule Metabolic Process Regulation Of Insulin Secretion	Calcium Ion-dependent Exocytosis Positive Regulation Of Vesicle Fusion Response To Calcium Ion
Pathways		Integration of energy metabolism Regulation of insulin secretion
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: NRXN1 POLR2E RAB1A SYT3	4 interactors: AP2A1 SNAP25 SYNCRIP SYT5
Entrez ID		6861	84258
HPRD ID		02870	08977
Ensembl ID			ENSG00000213023
Uniprot IDs		O00445 Q4FD32	Q9BQG1
PDB IDs
Enriched GO Terms of Interacting Partners?		Secretion By Cell Secretion Protein Complex Assembly Involved In Synapse Maturation Gamma-aminobutyric Acid Receptor Clustering Interleukin-8 Secretion Cargo Loading Into COPII-coated Vesicle Guanylate Kinase-associated Protein Clustering Neuroligin Clustering Vesicle Localization Gephyrin Clustering Synaptic Vesicle Clustering Interleukin-8 Production Neuronal Signal Transduction N-methyl-D-aspartate Receptor Clustering Vocal Learning Negative Regulation Of Filopodium Assembly Postsynaptic Membrane Assembly Synapse Maturation Regulation Of Grooming Behavior Presynaptic Membrane Assembly Postsynaptic Density Protein 95 Clustering Cargo Loading Into Vesicle Receptor Localization To Synapse Presynaptic Membrane Organization Auditory Behavior Cell Development Growth Hormone Secretion Organelle Localization Cerebellar Granule Cell Differentiation Establishment Of Localization In Cell Vocalization Behavior Prepulse Inhibition Neuron Cell-cell Adhesion Positive Regulation Of Synapse Maturation Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Glycoprotein Metabolic Process Mechanosensory Behavior Cerebellar Granular Layer Morphogenesis Viral Process Response To Auditory Stimulus Regulation Of Synapse Maturation Protein Localization To Synapse Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Positive Regulation Of Vesicle Fusion Membrane Assembly Regulation Of N-methyl-D-aspartate Selective Glutamate Receptor Activity Positive Regulation Of Synaptic Transmission, Glutamatergic COPII-coated Vesicle Budding Cerebellar Granular Layer Development	Synaptic Transmission Energy Reserve Metabolic Process Cell-cell Signaling Regulation Of Insulin Secretion Negative Regulation Of Hyaluronan Biosynthetic Process Regulation Of Peptide Hormone Secretion Regulation Of Hormone Secretion CRD-mediated MRNA Stabilization Vesicle-mediated Transport Energy Derivation By Oxidation Of Organic Compounds Exocytosis Synaptic Vesicle Docking Synaptic Vesicle Priming Regulation Of Protein Secretion Synaptic Vesicle Fusion To Presynaptic Membrane Generation Of Precursor Metabolites And Energy Neurotransmitter Uptake Establishment Of Localization In Cell Secretion By Cell Golgi To Endosome Transport Viral Process Cellular Localization Regulation Of Protein Transport Glutamate Secretion Secretion Regulation Of Defense Response To Virus By Virus Regulation Of Secretion MRNA Stabilization Regulation Of Establishment Of Protein Localization Clathrin-mediated Endocytosis Regulation Of Protein Localization Calcium Ion-dependent Exocytosis Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signaling Negative Regulation Of ERBB Signaling Pathway Long-term Synaptic Potentiation Vesicle Fusion Regulation Of MRNA Stability Synaptic Vesicle Exocytosis Regulation Of RNA Stability Acid Secretion Vesicle Docking Involved In Exocytosis Cell Differentiation Regulation Of Cellular Localization Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Organelle Fusion Regulation Of ERBB Signaling Pathway Vesicle Docking Regulation Of Defense Response To Virus Dicarboxylic Acid Transport
Tagcloud ?		activities altered animals app avp biological changed condition differentially enantiomers entire hypothalamic igf2 igfbp2 influences inhalation linalool microarray monitored nervous possess previous profile r rats relate restrained sst stressed
Tagcloud (Difference) ?		activities altered animals app avp biological changed condition differentially enantiomers entire hypothalamic igf2 igfbp2 influences inhalation linalool microarray monitored nervous possess previous profile r rats relate restrained sst stressed
Tagcloud (Intersection) ?