SURF2 and RPL5

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		SURF2	RPL5
Gene Name		surfeit 2	ribosomal protein L5
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component Nucleus Nucleolus Plasma Membrane	Nucleus Nucleolus Cytoplasm Cytosol Focal Adhesion Membrane Cytosolic Large Ribosomal Subunit Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Molecular_function	RNA Binding Structural Constituent Of Ribosome Protein Binding 5S RRNA Binding Poly(A) RNA Binding
	Biological Process	Biological_process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay RRNA Processing Translation Translational Initiation Translational Elongation Translational Termination SRP-dependent Cotranslational Protein Targeting To Membrane Gene Expression Viral Process Viral Life Cycle Viral Transcription Ribosomal Large Subunit Biogenesis Cellular Protein Metabolic Process
Pathways			Nonsense-Mediated Decay (NMD) Translation SRP-dependent cotranslational protein targeting to membrane Eukaryotic Translation Termination Peptide chain elongation Influenza Infection Viral mRNA Translation L13a-mediated translational silencing of Ceruloplasmin expression Influenza Life Cycle Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) Influenza Viral RNA Transcription and Replication GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Initiation Formation of a pool of free 40S subunits Eukaryotic Translation Elongation Cap-dependent Translation Initiation Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Activated partial thromboplastin time ( 22703881)	Height ( 20881960) Multiple sclerosis ( 19525955 17660530)
Protein-Protein Interactions		7 interactors: APP B4GALT3 NPTN PLAUR PRNP RPL5 ZNF331	21 interactors: CSNK2A1 CSNK2B DCC EIF5A HARS IPO13 IPO5 IPO7 KPNB1 MAP3K14 MDM2 NVL PDCD4 PPM1D SPP1 SURF2 TNIP1 TNPO1 TSC22D1 UPF2 VHL
Entrez ID		6835	6125
HPRD ID		15948	04699
Ensembl ID		ENSG00000148291	ENSG00000122406
Uniprot IDs		Q15527	A2RUM7 B3KTM6 P46777
PDB IDs			3J3B
Enriched GO Terms of Interacting Partners?		Cellular Copper Ion Homeostasis Copper Ion Homeostasis Cellular Metal Ion Homeostasis Cellular Cation Homeostasis Cellular Ion Homeostasis Metal Ion Homeostasis Urokinase Plasminogen Activator Signaling Pathway Cellular Chemical Homeostasis Ion Homeostasis Chemotaxis Synaptic Growth At Neuromuscular Junction Transition Metal Ion Homeostasis Cellular Homeostasis Collateral Sprouting In Absence Of Injury Negative Regulation Of Calcineurin-NFAT Signaling Cascade Collateral Sprouting Axon Midline Choice Point Recognition Post-translational Protein Modification Chemical Homeostasis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Copper Ion Axon Choice Point Recognition Negative Regulation Of Calcium-mediated Signaling Regulation Of Protein Metabolic Process Positive Regulation Of Long-term Neuronal Synaptic Plasticity Learning Or Memory Neuron Remodeling Negative Regulation Of Interleukin-17 Production Regulation Of Protein Phosphorylation Regulation Of Calcineurin-NFAT Signaling Cascade Cognition Cellular Calcium Ion Homeostasis Cellular Protein Metabolic Process Calcium Ion Homeostasis Attachment Of GPI Anchor To Protein Negative Regulation Of Activated T Cell Proliferation Positive Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Locomotion Regulation Of Phosphorylation Axon Guidance Negative Regulation Of Interleukin-2 Production Homeostatic Process Negative Regulation Of T Cell Receptor Signaling Pathway Response To Oxidative Stress Blood Coagulation Hemostasis Response To Copper Ion Suckling Behavior Regulation Of Phosphorus Metabolic Process Movement Of Cell Or Subcellular Component	Nucleocytoplasmic Transport Nuclear Transport Protein Localization To Nucleus Protein Import Into Nucleus Nuclear Import Protein Import Cytoplasmic Transport Protein Localization To Organelle Establishment Of Protein Localization To Organelle Negative Regulation Of Collateral Sprouting Ribosomal Protein Import Into Nucleus Protein Targeting NLS-bearing Protein Import Into Nucleus Intracellular Protein Transport Cellular Protein Localization Viral Process Apoptotic Process Establishment Of Protein Localization Regulation Of Cell Proliferation Programmed Cell Death Intracellular Transport Cell Death Death Protein Import Into Nucleus, Translocation Cellular Localization Response To External Stimulus Protein Localization Protein Transport Establishment Of Localization In Cell Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Cellular Response To UV-C Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Cellular Response To Vitamin B1 Negative Regulation Of Axonogenesis Chemotaxis MRNA Export From Nucleus Regulation Of MAPK Cascade Histidyl-tRNA Aminoacylation Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury RNA Export From Nucleus Regulation Of Catalytic Activity Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Negative Regulation Of Developmental Growth Spinal Cord Ventral Commissure Morphogenesis Netrin-activated Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Cell Growth Mitotic Cell Cycle Cellular Response To Hypoxia
Tagcloud ?			biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine imp impdh2 inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Difference) ?			biogenesis biosynthesis dehydrogenase deoxy disrupts dually genotoxic gtp guanine imp impdh2 inauzhin inosine inz mdm2 monophosphate notion nucleostemin pools ribonucleotide ribosomal rpl11 rps rrna rs sirt1 stressor suppresses surprisingly
Tagcloud (Intersection) ?