ST14 and RGS16

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ST14	RGS16
Gene Name		suppression of tumorigenicity 14 (colon carcinoma)	regulator of G-protein signaling 16
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Basolateral Plasma Membrane Extrinsic Component Of Plasma Membrane Extracellular Vesicular Exosome	Cytoplasm Plasma Membrane
	Molecular Function	Serine-type Endopeptidase Activity Serine-type Peptidase Activity	GTPase Activator Activity Protein Binding Calmodulin Binding
	Biological Process	Proteolysis Keratinocyte Differentiation	Visual Perception Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Termination Of G-protein Coupled Receptor Signaling Pathway Positive Regulation Of GTPase Activity
Pathways
Drugs		Urokinase Benzamidine
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CDCP1 F2RL1 HGF PDGFC PLAU RGS16 SPINT1	14 interactors: CREB3L2 CSK EGFR GDE1 GNA13 GNAI1 GNAI2 GNAI3 GNAO1 GNAQ GNAT1 LYN SRC ST14
Entrez ID		6768	6004
HPRD ID		06005	03945
Ensembl ID		ENSG00000149418	ENSG00000143333
Uniprot IDs		Q9Y5Y6	O15492
PDB IDs		1EAW 1EAX 2FMV 2GV6 2GV7 3BN9 3NCL 3NPS 3P8F 3P8G 3SO3 4IS5 4ISL 4ISN 4ISO	2BT2 2IK8
Enriched GO Terms of Interacting Partners?		Blood Coagulation Positive Regulation Of Phosphatidylinositol 3-kinase Signaling Hemostasis Regulation Of Phosphatidylinositol 3-kinase Signaling Interleukin-10 Secretion Negative Regulation Of Chemokine Secretion Positive Regulation Of Neutrophil Mediated Killing Of Gram-negative Bacterium Regulation Of Blood Coagulation Regulation Of Body Fluid Levels Regulation Of Cell Migration Wound Healing Regulation Of Cell Motility Regulation Of Wound Healing Regulation Of Locomotion Regulation Of Cellular Component Movement Response To Wounding Negative Regulation Of Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Toll-like Receptor 2 Signaling Pathway Chemokine Secretion Chemokine (C-C Motif) Ligand 2 Secretion Positive Regulation Of Eosinophil Degranulation Positive Regulation Of DNA Metabolic Process Positive Regulation Of Toll-like Receptor 3 Signaling Pathway Regulation Of Smooth Muscle Cell-matrix Adhesion Cell Migration Positive Regulation Of Phosphorylation Negative Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Positive Regulation Of Renin Secretion Into Blood Stream Myoblast Proliferation Interleukin-1 Beta Secretion Cell Motility Regulation Of Peptidyl-tyrosine Phosphorylation Interleukin-10 Production Regulation Of Catalytic Activity Positive Regulation Of Glomerular Filtration Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Renin Secretion Into Blood Stream Positive Regulation Of Cytokine Secretion Involved In Immune Response Mature Conventional Dendritic Cell Differentiation Interleukin-1 Secretion Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of Interleukin-6 Secretion Negative Regulation Of Signal Transduction Negative Regulation Of Endopeptidase Activity Interferon-gamma Secretion Negative Regulation Of Peptidase Activity Activation Of Protein Kinase Activity Positive Regulation Of Cell Projection Organization Cellular Response To Hepatocyte Growth Factor Stimulus Regulation Of Branching Involved In Salivary Gland Morphogenesis By Mesenchymal-epithelial Signaling	Platelet Activation Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Cell Activation Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Positive Regulation Of Catalytic Activity Cell Surface Receptor Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Catalytic Activity Response To Stress Signal Transduction Peptidyl-tyrosine Autophosphorylation G-protein Coupled Receptor Signaling Pathway Signaling Regulation Of Protein Kinase Activity Cell Differentiation Positive Regulation Of Metabolic Process Cell Communication Regulation Of Kinase Activity Regulation Of Intracellular Transport Regulation Of ERK1 And ERK2 Cascade Response To Organonitrogen Compound Adenylate Cyclase-inhibiting G-protein Coupled Receptor Signaling Pathway Protein Autophosphorylation Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of Kinase Activity Regulation Of Phosphorus Metabolic Process Organ Development Neuron Development Central Nervous System Development Cellular Response To Stimulus Positive Regulation Of Phospholipase Activity T Cell Costimulation Positive Regulation Of Transferase Activity System Development Regulation Of Phospholipase Activity Regulation Of Protein Phosphorylation Neurogenesis Peptidyl-tyrosine Phosphorylation Positive Regulation Of Lipase Activity Regulation Of MAPK Cascade Regulation Of MAP Kinase Activity Regulation Of Protein Transport Tissue Development Neuron Differentiation Regulation Of Establishment Of Protein Localization
Tagcloud ?		acetylation box coding compartment downregulates emt enables epcam epithelial esrp1 expected h358 h3k27 h3k9 h4 hdac hgf immunocytochemistry immunoprecipitation mesenchymal metastasis migratory note protease rab25 serine splicing stroma zeb1	aspc bxpc candidates coexpressing cooperate cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb profiling rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38
Tagcloud (Difference) ?		acetylation box coding compartment downregulates emt enables epcam epithelial esrp1 expected h358 h3k27 h3k9 h4 hdac hgf immunocytochemistry immunoprecipitation mesenchymal metastasis migratory note protease rab25 serine splicing stroma zeb1	aspc bxpc candidates coexpressing cooperate cross discovery downregulated exogenously inactivated inhibit inhibiting invasion metastases migration oncogenic p53 panc pancreatic prb profiling rb1 reoccurrence suppressors talk toward tumorigenesis viability wi38
Tagcloud (Intersection) ?