SPAG4 and TNMD

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SPAG4	TNMD
Description		sperm associated antigen 4	tenomodulin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nuclear Inner Membrane Cytoplasm Cytoskeleton Cilium Membrane Motile Cilium Meiotic Nuclear Membrane Microtubule Tethering Complex Cell Projection	Nucleus Nuclear Envelope Cytoplasm Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Protein-membrane Adaptor Activity	Protein Binding
	Biological Process	Spermatogenesis Cell Differentiation	Endothelial Cell Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Angiogenesis
Pathways
Drugs
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		24 interacting genes: ABHD16A ASGR1 BMP10 CSGALNACT1 ERMP1 GOSR2 IGFBP5 MS4A13 NRM ODF1 PAXIP1 PGA4 PLN PTPN9 RUSF1 SCAMP4 SCD SEC22A SUN5 TMEM187 TMEM60 TNMD TRARG1 TSPO2	17 interacting genes: AMIGO1 ARL13B BCL2L13 BNIP3 BNIP3L CD33 CREB3L1 FAM209A FCGR1A GGT6 HHLA2 KIR3DL3 LMNA MYG1 SPAG4 TMEM106A TMEM79
Entrez ID		6676	64102
HPRD ID		04330	02352
Ensembl ID		ENSG00000061656	ENSG00000000005
Uniprot IDs		A0A7P0Z4G5 Q9NPE6	Q9H2S6
PDB IDs
Enriched GO Terms of Interacting Partners?			Mitochondrial Protein Catabolic Process Negative Regulation Of Membrane Potential Nuclear Envelope Negative Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Permeabilization Membrane Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Cellular Response To Oxygen Levels Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Tumor Necrosis Factor Production Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Autophagosome Adaptor Activity High-affinity IgG Receptor Activity Nuclear Inner Membrane Regulation Of Autophagy Of Mitochondrion Mitophagy Regulation Of Mitochondrial Membrane Permeability Fc Receptor Signaling Pathway
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