TNMD and HHLA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNMD	HHLA2
Description		tenomodulin	HHLA2 member of B7 family
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Membrane	External Side Of Plasma Membrane Membrane
	Molecular Function	Protein Binding	Signaling Receptor Binding Protein Binding
	Biological Process	Endothelial Cell Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Angiogenesis	Regulation Of Cytokine Production Positive Regulation Of Cytokine Production T Cell Costimulation Positive Regulation Of Activated T Cell Proliferation T Cell Receptor Signaling Pathway Regulation Of T Cell Activation Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Drugs
Diseases
GWAS			Regular attendance at a religious group ( 29970889)
Interacting Genes		17 interacting genes: AMIGO1 ARL13B BCL2L13 BNIP3 BNIP3L CD33 CREB3L1 FAM209A FCGR1A GGT6 HHLA2 KIR3DL3 LMNA MYG1 SPAG4 TMEM106A TMEM79	14 interacting genes: AQP9 BRICD5 BTNL8 C3orf52 ERMP1 FAM3C NIPAL4 NRM PGA4 RPRM SMCO4 TMEM140 TNMD UNC93B1
Entrez ID		64102	11148
HPRD ID		02352	05082
Ensembl ID		ENSG00000000005	ENSG00000114455
Uniprot IDs		Q9H2S6	C9J7D0 Q9UM44
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Negative Regulation Of Membrane Potential Nuclear Envelope Negative Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Permeabilization Membrane Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Cellular Response To Oxygen Levels Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Tumor Necrosis Factor Production Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Autophagosome Adaptor Activity High-affinity IgG Receptor Activity Nuclear Inner Membrane Regulation Of Autophagy Of Mitochondrion Mitophagy Regulation Of Mitochondrial Membrane Permeability Fc Receptor Signaling Pathway
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