TNMD and TMEM106A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TNMD	TMEM106A
Description		tenomodulin	transmembrane protein 106A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Cytoplasm Membrane	Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Endothelial Cell Morphogenesis Negative Regulation Of Endothelial Cell Proliferation Negative Regulation Of Angiogenesis	Immune System Process Glycoprotein Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Macrophage Activation Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process
Pathways
Drugs
Diseases
GWAS			Blood protein levels ( 30072576)
Interacting Genes		17 interacting genes: AMIGO1 ARL13B BCL2L13 BNIP3 BNIP3L CD33 CREB3L1 FAM209A FCGR1A GGT6 HHLA2 KIR3DL3 LMNA MYG1 SPAG4 TMEM106A TMEM79	12 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM107 TMEM128 TMEM86B TNMD TSPAN4
Entrez ID		64102	113277
HPRD ID		02352	11315
Ensembl ID		ENSG00000000005	ENSG00000184988
Uniprot IDs		Q9H2S6	B7Z779 Q96A25
PDB IDs
Enriched GO Terms of Interacting Partners?		Mitochondrial Protein Catabolic Process Negative Regulation Of Membrane Potential Nuclear Envelope Negative Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Permeabilization Membrane Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Positive Regulation Of Mitochondrial Membrane Permeability Positive Regulation Of Membrane Permeability Cellular Response To Oxygen Levels Fc-gamma Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Regulation Of Tumor Necrosis Factor Production Regulation Of Release Of Cytochrome C From Mitochondria Mitochondrion Autophagosome Adaptor Activity High-affinity IgG Receptor Activity Nuclear Inner Membrane Regulation Of Autophagy Of Mitochondrion Mitophagy Regulation Of Mitochondrial Membrane Permeability Fc Receptor Signaling Pathway
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