BNIP2 and BNIPL

Number of citations of the paper that reports this interaction (PMID 12901880)
4

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		BNIP2	BNIPL
Gene Name		BCL2/adenovirus E1B 19kDa interacting protein 2	BCL2/adenovirus E1B 19kD interacting protein like
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Envelope Cytoplasm Cytosol Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm	Nucleus Cytosol
	Molecular Function	GTPase Activator Activity Calcium Ion Binding Protein Binding Identical Protein Binding	Protein Binding Identical Protein Binding
	Biological Process	Apoptotic Process Muscle Cell Differentiation Negative Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Positive Regulation Of Muscle Cell Differentiation	Apoptotic Process Negative Regulation Of Cell Proliferation Regulation Of Growth Rate
Pathways		CDO in myogenesis Myogenesis
Drugs
Diseases
GWAS			Chronic kidney disease ( 20383146)
Protein-Protein Interactions		13 interactors: ARHGAP1 ARHGAP8 BCL2 BNIPL CDC42 CREB3 FATE1 FGFR1 FRK KLC1 MYO5B NCBP1 UPK1B	14 interactors: ARHGAP1 BAX BCL2 BCL2L1 BNIP2 CDC42 FKBP8 GFER MIF NME2 PXDN PYCR1 RECQL5 SNAPIN
Entrez ID		663	149428
HPRD ID		04481	16557
Ensembl ID		ENSG00000140299	ENSG00000163141
Uniprot IDs		J3KN59 Q12982	Q7Z465
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Heterodimerization Activity Regulation Of Cell Proliferation Positive Regulation Of Catalytic Activity Gland Morphogenesis Regulation Of Intracellular Signal Transduction Epithelial Cell Differentiation Hair Follicle Morphogenesis Regulation Of Growth Epidermis Morphogenesis Salivary Gland Morphogenesis Positive Regulation Of Signal Transduction Salivary Gland Development Epidermis Development Skin Morphogenesis Neural Nucleus Development Cell Fate Commitment Exocrine System Development Positive Regulation Of Striated Muscle Tissue Development Positive Regulation Of Muscle Tissue Development Positive Regulation Of Metabolic Process Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Negative Regulation Of Cellular PH Reduction Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity CD8-positive, Alpha-beta T Cell Lineage Commitment Negative Regulation Of Retinal Cell Programmed Cell Death Regulation Of Catalytic Activity Cellular Localization Positive Regulation Of Phosphorylation Positive Regulation Of Peptidyl-serine Phosphorylation Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Cellular Metabolic Process Midbrain Development Positive Regulation Of Muscle Cell Differentiation Adherens Junction Organization Regulation Of Cell Cycle Hair Follicle Development Stress Granule Disassembly Fibroblast Growth Factor Receptor Signaling Pathway Involved In Orbitofrontal Cortex Development Positive Regulation Of Hair Follicle Cell Proliferation Regulation Of Lateral Mesodermal Cell Fate Specification Release From Viral Latency Hair Cycle Process Renal System Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Intracellular Transport Regulation Of Signal Transduction Positive Regulation Of MAPK Cascade Regulation Of Peptidyl-serine Phosphorylation	Regulation Of Mitochondrial Membrane Potential Regulation Of Protein Heterodimerization Activity Negative Regulation Of Cell Death Regulation Of Cell Death Ovarian Follicle Development Positive Regulation Of Signal Transduction Ovulation Cycle Process Negative Regulation Of Apoptotic Process Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Programmed Cell Death Female Gonad Development Regulation Of Apoptotic Process Ovulation Cycle Development Of Primary Female Sexual Characteristics Release Of Cytochrome C From Mitochondria Regulation Of Nitrogen Utilization Regulation Of Mitochondrial Membrane Permeability Regulation Of Membrane Permeability Regulation Of Protein Binding Mitochondrial Transport Regulation Of Intrinsic Apoptotic Signaling Pathway Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Response To Gamma Radiation Male Sex Differentiation Positive Regulation Of Intracellular Signal Transduction Neuron Apoptotic Process Regulation Of Signal Transduction Regulation Of Cell Development Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Mitochondrial Membrane Organization Neuron Death Positive Regulation Of Cell Development Gonad Development Apoptotic Mitochondrial Changes Development Of Primary Sexual Characteristics Regulation Of Neuron Apoptotic Process Positive Regulation Of Intracellular Transport Germ Cell Development Regulation Of Signaling Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Peptidyl-serine Phosphorylation Regulation Of Binding Regulation Of Cellular Localization Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Regulation Of Membrane Potential Positive Regulation Of Muscle Cell Differentiation Regulation Of Neuron Death Negative Regulation Of Signal Transduction Sex Differentiation Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Tagcloud ?		activator antiapoptotic attenuated bcl blocks cleavage cytotoxicity deacetylase imply inhibits intensified mediate mpp nad neuroprotective parp participates phenylpyridinium possibly resveratrol sh shrna sirna sirt1 sirtuin sy5y transfected transfection xl	allowing alters antagonization antagonize antiapoptotic bag1 bcl bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby
Tagcloud (Difference) ?		activator attenuated blocks cleavage cytotoxicity deacetylase imply inhibits intensified mediate mpp nad neuroprotective parp participates phenylpyridinium possibly resveratrol sh shrna sirna sirt1 sirtuin sy5y transfected transfection xl	allowing alters antagonization antagonize bag1 bcl2l13 becn1 bmf bnip1 bnip3 clu conditional considering erbb2 influences influencing master mcl members proapoptotic prognosis prototypic relevance remission substitute tegt whereby
Tagcloud (Intersection) ?		antiapoptotic bcl