SNAI1 and FBXL14

Number of citations of the paper that reports this interaction (PMID 19955572)
19

Data Source:
BioGRID (pull down)

		SNAI1	FBXL14
Gene Name		snail family zinc finger 1	F-box and leucine-rich repeat protein 14
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleoplasm Cytoplasm Golgi Apparatus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription Protein Binding Kinase Binding Metal Ion Binding	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Osteoblast Differentiation Mesoderm Formation Epithelial To Mesenchymal Transition Positive Regulation Of Epithelial To Mesenchymal Transition Negative Regulation Of Vitamin D Biosynthetic Process Cell Migration Positive Regulation Of Cell Migration Hair Follicle Morphogenesis Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Transcription, DNA-templated Palate Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Left/right Pattern Formation Notch Signaling Involved In Heart Development Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Tight Junction Assembly	Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Pathways
Drugs
Diseases
GWAS		Psoriasis ( 20953189)
Protein-Protein Interactions		19 interactors: ACTN2 CTDSP1 CTDSP2 CTDSPL FBXL14 FBXL5 GSK3B HIST1H3A HOXD4 KRT31 KRT40 KRTAP10-3 LATS2 MID2 MTUS2 NOTCH1 NOTCH2NL RCOR1 TRIM23	1 interactors: SNAI1
Entrez ID		6615	144699
HPRD ID		05025	10949
Ensembl ID		ENSG00000124216	ENSG00000171823
Uniprot IDs		O95863	Q8N1E6
PDB IDs		2Y48
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Protein Phosphorylation Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Phosphorylation Protein Localization To Microtubule Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Metabolic Process Cellular Protein Modification Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Protein Localization To Cytoskeleton Cellular Protein Metabolic Process Negative Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cell Cycle Regulation Of Hematopoietic Progenitor Cell Differentiation Negative Regulation Of Protein Metabolic Process Negative Regulation Of Neuron Differentiation Negative Regulation Of Wnt Signaling Pathway Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Canonical Wnt Signaling Pathway Regulation Of Cell Cycle Phase Transition Protein Ubiquitination Regulation Of Protein Phosphorylation Wound Healing Positive Regulation Of Stem Cell Differentiation Protein Modification By Small Protein Conjugation Epithelial To Mesenchymal Transition Epidermis Development Venous Endothelial Cell Differentiation Notch Signaling Pathway Involved In Regulation Of Secondary Heart Field Cardioblast Proliferation Protein Metabolic Process Negative Regulation Of Neurogenesis Regulation Of Developmental Growth Response To Wounding Regulation Of Wnt Signaling Pathway Regulation Of Cellular Protein Metabolic Process Regulation Of Phosphorylation Negative Regulation Of Cell Development Negative Regulation Of Type B Pancreatic Cell Development Vasculogenesis Involved In Coronary Vascular Morphogenesis Cardiac Right Atrium Morphogenesis Mitral Valve Formation Superior Temporal Gyrus Development Negative Regulation Of Biosynthetic Process Keratinocyte Differentiation Regulation Of Nitrogen Compound Metabolic Process Cellular Metabolic Process Regulation Of Protein Metabolic Process	Negative Regulation Of Cell Differentiation Involved In Embryonic Placenta Development Negative Regulation Of Vitamin D Biosynthetic Process Notch Signaling Involved In Heart Development Regulation Of Tight Junction Assembly Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Regulation Of Vitamin Metabolic Process Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Left/right Pattern Formation Negative Regulation Of Steroid Biosynthetic Process Negative Regulation Of Signal Transduction By P53 Class Mediator Negative Regulation Of Steroid Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Negative Regulation Of Embryonic Development Positive Regulation Of Epithelial To Mesenchymal Transition Cell Differentiation Involved In Embryonic Placenta Development Hair Follicle Morphogenesis Epidermis Morphogenesis Negative Regulation Of Lipid Biosynthetic Process Regulation Of Signal Transduction By P53 Class Mediator Skin Morphogenesis Positive Regulation Of Stem Cell Differentiation Epithelial To Mesenchymal Transition Regulation Of Epithelial To Mesenchymal Transition Regulation Of Cell Junction Assembly Regulation Of Steroid Biosynthetic Process Negative Regulation Of Lipid Metabolic Process Mesoderm Formation Mesoderm Morphogenesis Hair Follicle Development Hair Cycle Process Regulation Of Steroid Metabolic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Hair Cycle Palate Development Mesenchymal Cell Development Regulation Of Embryonic Development Embryonic Placenta Development Regulation Of Response To DNA Damage Stimulus Formation Of Primary Germ Layer Regulation Of Lipid Biosynthetic Process Mesenchymal Cell Differentiation Notch Signaling Pathway Osteoblast Differentiation Mesoderm Development Regulation Of Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Morphogenesis Involved In Differentiation Gastrulation Placenta Development
Tagcloud ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	achieve adaptor bhlh box cul1 degraded destruction e3 elucidated embryo emt helix inducers leucine ligase lights malignancy mesenchymal motility rationale repeat scf shedding skp1 transdifferentiation transducin trcp triggers twist
Tagcloud (Difference) ?		aberrations apart aspect ccnd1 clinicopathological copy covered encompassed endometrial erbb1 erbb2 erbb3 erbb4 esr1 frequent infiltration insufficient myometrial pakt1 pgr pik3ca prom1 rad21 rad27 runx1 scgb2a2 snai2 top2a younger	achieve adaptor bhlh box cul1 degraded destruction e3 elucidated embryo emt helix inducers leucine ligase lights malignancy mesenchymal motility rationale repeat scf shedding skp1 transdifferentiation transducin trcp triggers twist
Tagcloud (Intersection) ?