SMPD2 and PITPNC1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SMPD2	PITPNC1
Description		sphingomyelin phosphodiesterase 2	phosphatidylinositol transfer protein cytoplasmic 1
Image			No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Plasma Membrane Caveola Membrane Cell Periphery	Nucleus Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Catalytic Activity Sphingomyelin Phosphodiesterase Activity Protein Binding Phosphoric Diester Hydrolase Activity Hydrolase Activity Metal Ion Binding	Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Phosphatidic Acid Binding Phosphatidylglycerol Binding Phosphatidic Acid Transfer Activity
	Biological Process	Lipid Metabolic Process Sphingolipid Metabolic Process Ceramide Metabolic Process Sphingomyelin Metabolic Process Sphingomyelin Catabolic Process Response To Mechanical Stimulus Sphingolipid Catabolic Process Intracellular Signal Transduction Ceramide Biosynthetic Process	Lipid Transport Signal Transduction Phospholipid Transport Intermembrane Lipid Transfer
Pathways		Ceramide signalling TNFR1-mediated ceramide production Glycosphingolipid catabolism
Drugs
Diseases
GWAS		Height ( 18391951)	Blood urea nitrogen levels ( 29403010 31152163) Body size at age 10 ( 32376654) Chronic central serous retinopathy ( 30073298) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Plasma selenium concentration ( 33382417) Pulmonary function ( 23932459) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum immune biomarker levels ( 32066700) Type 2 diabetes ( 32499647) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		15 interacting genes: ARFIP1 CCN1 COQ8A GAD2 NDRG4 PBX3 PGRMC2 PIK3CG PITPNC1 SLC10A1 SLC7A8 STAR TMEM14B TMEM167B TMEM31	14 interacting genes: AGTRAP ANKS6 CACFD1 CMTM5 DGAT2L6 GSG1 HTATIP2 KATNAL1 MAL2 REEP5 SCAMP5 SMPD2 SYP TNFRSF10D
Entrez ID		6610	26207
HPRD ID		04608	05504
Ensembl ID		ENSG00000135587	ENSG00000154217
Uniprot IDs		O60906	A0A0C4DGP0 Q9UKF7
PDB IDs		8J2F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?