PITPNC1 and CACFD1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PITPNC1	CACFD1
Description		phosphatidylinositol transfer protein cytoplasmic 1	calcium channel flower domain containing 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Endosome Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Plasma Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Synapse Recycling Endosome
	Molecular Function	Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Phosphatidic Acid Binding Phosphatidylglycerol Binding Phosphatidic Acid Transfer Activity	Protein Binding
	Biological Process	Lipid Transport Signal Transduction Phospholipid Transport Intermembrane Lipid Transfer	Vesicle-mediated Transport
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010 31152163) Body size at age 10 ( 32376654) Chronic central serous retinopathy ( 30073298) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Plasma selenium concentration ( 33382417) Pulmonary function ( 23932459) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum immune biomarker levels ( 32066700) Type 2 diabetes ( 32499647) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Gut microbiota (functional units) ( 27694959)
Interacting Genes		14 interacting genes: AGTRAP ANKS6 CACFD1 CMTM5 DGAT2L6 GSG1 HTATIP2 KATNAL1 MAL2 REEP5 SCAMP5 SMPD2 SYP TNFRSF10D	11 interacting genes: CREB3 HSFX1 HSFX2 LDAF1 MTERF3 NDRG4 PITPNC1 PNKP RBFA SH3GLB1 SNCA
Entrez ID		26207	11094
HPRD ID		05504	12974
Ensembl ID		ENSG00000154217	ENSG00000160325
Uniprot IDs		A0A0C4DGP0 Q9UKF7	Q9UGQ2
PDB IDs
Enriched GO Terms of Interacting Partners?			Negative Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Mitochondrial Outer Membrane Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Regulation Of Platelet-derived Growth Factor Receptor Signaling Pathway Fatty Acid Binding Positive Regulation Of Deacetylase Activity Protein Localization To Vacuolar Membrane
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