PITPNC1 and ANKS6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PITPNC1	ANKS6
Description		phosphatidylinositol transfer protein cytoplasmic 1	ankyrin repeat and sterile alpha motif domain containing 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol	Cytoplasm Cilium Cell Projection Ciliary Inversin Compartment
	Molecular Function	Protein Binding Phospholipid Transporter Activity Lipid Binding Phosphatidylcholine Transporter Activity Phosphatidylinositol Transfer Activity Phosphatidylinositol Binding Phosphatidic Acid Binding Phosphatidylglycerol Binding Phosphatidic Acid Transfer Activity	Protein Binding
	Biological Process	Lipid Transport Signal Transduction Phospholipid Transport Intermembrane Lipid Transfer	In Utero Embryonic Development Kidney Development Determination Of Left/right Symmetry Heart Development
Pathways
Drugs
Diseases
GWAS		Blood urea nitrogen levels ( 29403010 31152163) Body size at age 10 ( 32376654) Chronic central serous retinopathy ( 30073298) Chronotype ( 30696823) Diisocyanate-induced asthma ( 25918132) Estimated glomerular filtration rate ( 31152163) Morning person ( 30696823) Plasma selenium concentration ( 33382417) Pulmonary function ( 23932459) Response to protease inhibitor treatment in hepatitis c (peak serum total bilirubin levels) ( 24503447) Serum immune biomarker levels ( 32066700) Type 2 diabetes ( 32499647) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Autism spectrum disorder ( 34069769) Body mass index ( 28892062)
Interacting Genes		14 interacting genes: AGTRAP ANKS6 CACFD1 CMTM5 DGAT2L6 GSG1 HTATIP2 KATNAL1 MAL2 REEP5 SCAMP5 SMPD2 SYP TNFRSF10D	19 interacting genes: AGTRAP APP BCL2L2 BET1 C1GALT1 C5 EMD EMP1 IGFBP5 MARCHF5 PITPNC1 RTP2 SMIM1 STRIT1 STX7 TMEM120B TMEM60 VAMP4 VEZT
Entrez ID		26207	203286
HPRD ID		05504	18012
Ensembl ID		ENSG00000154217	ENSG00000165138
Uniprot IDs		A0A0C4DGP0 Q9UKF7	B3KXP1 Q68DC2
PDB IDs			4NL9
Enriched GO Terms of Interacting Partners?			Membrane SNARE Complex
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