BOLL and AGRN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		BOLL	AGRN
Description		boule RNA binding protein	agrin
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Extracellular Region Basement Membrane Golgi Lumen Plasma Membrane Membrane Extracellular Matrix Lysosomal Lumen Synapse Extracellular Exosome
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding	Dystroglycan Binding Structural Constituent Of Cytoskeleton Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Sialic Acid Binding Chondroitin Sulfate Binding Laminin Binding Heparan Sulfate Proteoglycan Binding Metal Ion Binding
	Biological Process	Regulation Of Translation Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation Meiotic Cell Cycle 3'-UTR-mediated MRNA Stabilization	Cytoskeleton Organization Signal Transduction G Protein-coupled Acetylcholine Receptor Signaling Pathway Nervous System Development Neuromuscular Junction Development Regulation Of Synaptic Assembly At Neuromuscular Junction Cell Differentiation Receptor Clustering Positive Regulation Of GTPase Activity Clustering Of Voltage-gated Sodium Channels Positive Regulation Of Synaptic Assembly At Neuromuscular Junction Positive Regulation Of Transcription By RNA Polymerase II Synapse Organization Positive Regulation Of Filopodium Assembly Membrane Organization Synaptic Signaling
Pathways			Glycosaminoglycan-protein linkage region biosynthesis HS-GAG biosynthesis HS-GAG biosynthesis HS-GAG degradation Integrin cell surface interactions Non-integrin membrane-ECM interactions ECM proteoglycans ECM proteoglycans Defective B4GALT7 causes EDS, progeroid type Defective B3GAT3 causes JDSSDHD Defective EXT2 causes exostoses 2 Defective EXT1 causes exostoses 1, TRPS2 and CHDS NCAM1 interactions Defective B3GALT6 causes EDSP2 and SEMDJL1 Attachment and Entry Attachment and Entry Retinoid metabolism and transport Respiratory syncytial virus (RSV) attachment and entry RSV-host interactions Formation of the dystrophin-glycoprotein complex (DGC)
Drugs
Diseases			Congenital myasthenic syndrome
GWAS		Asthma ( 31361310) Autism spectrum disorder or schizophrenia ( 28540026) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Crohn's disease ( 28067908) Idiopathic dilated cardiomyopathy ( 29495422) Intracranial aneurysm ( 18997786) Morning person ( 30696823) Rheumatoid arthritis ( 32868391) Schizophrenia ( 29483656 25056061) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)
Interacting Genes		37 interacting genes: AGRN ARID5A ATXN2L C1orf94 CBX2 DAZ1 DAZ4 DCANP1 EHHADH FAM168A FOXD4L1 HNRNPLL HYAL3 HYPK INO80B KRTAP19-3 NAF1 NPBWR2 PATZ1 PHF1 POGZ POM121 PRR34 RBFOX2 RBPMS RBPMS2 RHOXF2 SEMA3B SERF2 SNRPC SPMIP2 SYCE1L TCEA2 TFG ZBTB32 ZC3H10 ZNF385C	11 interacting genes: ATN1 ATXN7 BOLL CACNA1A DAG1 GFI1B HOXA1 MAGED1 NUFIP2 TEPSIN UBC
Entrez ID		66037	375790
HPRD ID		07314	10550
Ensembl ID		ENSG00000152430	ENSG00000188157
Uniprot IDs		Q8N9W6	O00468
PDB IDs			8S9P
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding MRNA Binding Regulation Of RNA Splicing Regulation Of MRNA Metabolic Process RNA Binding Nucleus Translation Activator Activity Regulation Of Alternative MRNA Splicing, Via Spliceosome	Nuclear Matrix
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