TRAK2 and OGT

Number of citations of the paper that reports this interaction (PMID 12435728)
34

Data Source:
HPRD (in vitro)

		TRAK2	OGT
Gene Name		trafficking protein, kinesin binding 2	O-linked N-acetylglucosamine (GlcNAc) transferase
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Early Endosome Plasma Membrane	Histone Acetyltransferase Complex Nucleus Nucleoplasm Cytoplasm Mitochondrion Microtubule Organizing Center Cytosol Plasma Membrane MLL5-L Complex
	Molecular Function	Receptor Binding Protein Binding Enzyme Binding GABA Receptor Binding	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Enzyme Activator Activity Acetylglucosaminyltransferase Activity Protein N-acetylglucosaminyltransferase Activity Histone Acetyltransferase Activity (H4-K5 Specific) Histone Acetyltransferase Activity (H4-K8 Specific) Histone Acetyltransferase Activity (H4-K16 Specific) Protein O-GlcNAc Transferase Activity
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Protein O-linked Glycosylation Protein Targeting	Regulation Of Glycolytic Process Chromatin Organization Protein O-linked Glycosylation Apoptotic Process Signal Transduction Response To Nutrient Positive Regulation Of Granulocyte Differentiation Negative Regulation Of Protein Ubiquitination Response To Insulin Circadian Regulation Of Gene Expression Regulation Of Rac Protein Signal Transduction Positive Regulation Of Catalytic Activity Histone H4-K5 Acetylation Histone H4-K8 Acetylation Histone H4-K16 Acetylation Positive Regulation Of Proteolysis Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Insulin Receptor Signaling Pathway Phosphatidylinositol-mediated Signaling Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Histone H3-K27 Methylation Cellular Response To Retinoic Acid Histone H3-K4 Trimethylation Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis
Pathways			Chromatin modifying enzymes Chromatin organization HATs acetylate histones
Drugs
Diseases
GWAS
Protein-Protein Interactions		3 interactors: GABRB2 KCNJ2 OGT	18 interactors: CSNK2A1 GSK3B HCFC1 MAPT MGEA5 NUP62 NUP62CL PHC3 PSG1 SIN3A SNAP91 SP1 SRF TAB1 TET2 TRAK1 TRAK2 YES1
Entrez ID		66008	8473
HPRD ID		09547	02222
Ensembl ID		ENSG00000115993	ENSG00000147162
Uniprot IDs		O60296	O15294
PDB IDs			1W3B 3PE3 3PE4 3TAX 4AY5 4AY6 4GYW 4GYY 4GZ3 4GZ5 4GZ6
Enriched GO Terms of Interacting Partners?		Regulation Of Skeletal Muscle Contraction Via Regulation Of Action Potential Relaxation Of Skeletal Muscle Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Regulation Of Resting Membrane Potential Cellular Potassium Ion Homeostasis Positive Regulation Of Granulocyte Differentiation Cellular Response To Histamine Regulation Of Skeletal Muscle Contraction Synaptic Transmission, GABAergic Membrane Repolarization During Cardiac Muscle Cell Action Potential Membrane Repolarization During Action Potential Positive Regulation Of Histone H3-K27 Methylation Response To Histamine Cellular Chemical Homeostasis Histone H3-K4 Trimethylation Membrane Depolarization During Cardiac Muscle Cell Action Potential Histone H4-K5 Acetylation Histone H4-K8 Acetylation Membrane Repolarization Relaxation Of Cardiac Muscle Regulation Of Histone H3-K27 Methylation Potassium Ion Homeostasis Synaptic Transmission Histone H4-K16 Acetylation Positive Regulation Of Histone H3-K4 Methylation Positive Regulation Of Potassium Ion Transmembrane Transport Cellular Homeostasis Cellular Response To Ammonium Ion Relaxation Of Muscle Regulation Of Membrane Repolarization Regulation Of Heart Rate By Cardiac Conduction Regulation Of Histone H3-K4 Methylation Potassium Ion Import Magnesium Ion Transport Regulation Of Glycolytic Process Peptidyl-lysine Trimethylation Cardiac Muscle Cell Action Potential Involved In Contraction Response To Organonitrogen Compound Positive Regulation Of Potassium Ion Transport Gamma-aminobutyric Acid Signaling Pathway Chemical Homeostasis Histone H3-K4 Methylation Cell-cell Signaling Membrane Depolarization During Action Potential Innervation Regulation Of Rac Protein Signal Transduction Cardiac Muscle Cell Action Potential Positive Regulation Of Histone Methylation Regulation Of Potassium Ion Transmembrane Transport Inner Ear Receptor Cell Development	Positive Regulation Of Cell Growth Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Axon Extension Regulation Of Axon Extension Positive Regulation Of Growth Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Axonogenesis Positive Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Protein Localization Positive Regulation Of Cellular Metabolic Process Regulation Of Cellular Component Organization Protein O-linked Glycosylation Protein Transport Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Establishment Of Protein Localization Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Rhythmic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Aging Regulation Of RNA Metabolic Process Developmental Process Positive Regulation Of Cellular Biosynthetic Process Regulation Of Protein Complex Assembly Regulation Of Cell Growth Regulation Of Cell Size Megakaryocyte Differentiation Cell Morphogenesis Involved In Differentiation Trophectodermal Cell Differentiation Histone Modification Anatomical Structure Morphogenesis Regulation Of Gene Expression Cellular Protein Modification Process Positive Regulation Of Developmental Growth Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Response To Organic Substance Negative Regulation Of Cellular Protein Metabolic Process Cellular Response To Organic Substance Neuron Projection Development Positive Regulation Of Protein Complex Assembly Glycoprotein Metabolic Process Negative Regulation Of Protein Metabolic Process Blastocyst Formation Regulation Of Metabolic Process In Utero Embryonic Development
Tagcloud ?		ancestor armc10 armcx armcx1 cluster comparisons conservation dynamics enhancers eutherian evolved fission kif5 localise localises mammals miro1 mitochondria mitochondrial moving neuroprotective neurotransmission organisation prevents retrotransposition syntenic trafficking underscore vertebrates	acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Difference) ?		ancestor armc10 armcx armcx1 cluster comparisons conservation dynamics enhancers eutherian evolved fission kif5 localise localises mammals miro1 mitochondria mitochondrial moving neuroprotective neurotransmission organisation prevents retrotransposition syntenic trafficking underscore vertebrates	acetylglucosamine aggregates autophagic autophagosome autophagosomes autophagy caenorhabditis defective elegans endosomes facilitates flux glcnac glcnacylated glcnacylation integrates lysosomes mammalian mediates mutating nutrient promotes regulates reveals snap snare starvation transferase
Tagcloud (Intersection) ?