SLC18A2 and TOMM6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC18A2	TOMM6
Description		solute carrier family 18 member A2	translocase of outer mitochondrial membrane 6
Image
GO Annotations	Cellular Component	Centrosome Plasma Membrane Synaptic Vesicle Membrane Axon Dendrite Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Cell Projection Terminal Bouton Synapse Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane TOM Complex
	Molecular Function	Serotonin:sodium:chloride Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Monoamine:proton Antiporter Activity Transmembrane Transporter Activity	Protein Binding
	Biological Process	Response To Amphetamine Serotonin Secretion By Mast Cell Histamine Secretion By Mast Cell Neurotransmitter Transport Serotonin Transport Chemical Synaptic Transmission Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Serotonin Uptake Histamine Uptake Establishment Of Localization In Cell Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Somato-dendritic Dopamine Secretion Proton Transmembrane Transport Negative Regulation Of Reactive Oxygen Species Biosynthetic Process	Protein Transport Protein Insertion Into Mitochondrial Outer Membrane
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle	Mitochondrial protein import PINK1-PRKN Mediated Mitophagy
Drugs		Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS		Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925) Serum metabolite levels ( 33031748)	Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 NKG7 SLC61A1 SLC7A1 TMEM109 TOMM6	14 interacting genes: AQP6 C1orf159 CD68 CERS4 ERGIC3 FFAR3 GLP1R HUNK ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B
Entrez ID		6571	100188893
HPRD ID		01896	19464
Ensembl ID		ENSG00000165646	ENSG00000214736
Uniprot IDs		Q05940	Q96B49
PDB IDs		8JSW 8JSX 8JT5 8JT9 8JTA 8JTB 8JTC 8T69 8T6A 8T6B 8THR 8UCJ 8UCK 8UCL 8UCM 8UCN 8UCO 8UCP 8WLJ 8WLK 8WLL 8WLM 8WRD 8WRE 8WVG 8X3K 8XO9 8XOA 8XOB 9KQ8 9KQA 9KQE	7CK6 7CP9 7VBY 7VC4 7VD2 7VDD 8XVA 9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Protein Kinase CK2 Complex Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process PcG Protein Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Wnt Signaling Pathway Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Response To Stress Interleukin-8 Receptor Activity Interleukin-8-mediated Signaling Pathway Lysine Transport L-histidine Import Across Plasma Membrane Regulation Of Chromosome Separation	Post-translational Protein Targeting To Membrane, Translocation Hormone Secretion Hormone Transport Transmembrane Transport Membrane Intracellular Protein Transmembrane Transport Signal Release Nitrate Transmembrane Transporter Activity Glucagon-like Peptide 1 Receptor Activity Negative Regulation Of Blood Pressure Serotonin Secretion By Mast Cell Somato-dendritic Dopamine Secretion Regulation Of Hormone Levels PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Thyroid-stimulating Hormone Secretion Aminergic Neurotransmitter Loading Into Synaptic Vesicle Retrograde Transporter Complex, Golgi To ER Protein Transmembrane Transport Glucagon Receptor Activity Histamine Uptake Serotonin:sodium:chloride Symporter Activity
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