SLC18A2

Description		solute carrier family 18 member A2
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GO Annotations	Cellular Component	Centrosome Plasma Membrane Synaptic Vesicle Membrane Axon Dendrite Transport Vesicle Membrane Secretory Granule Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Cell Projection Terminal Bouton Synapse Clathrin-sculpted Monoamine Transport Vesicle Membrane Dopaminergic Synapse
	Molecular Function	Serotonin:sodium:chloride Symporter Activity Protein Binding Monoamine Transmembrane Transporter Activity Monoamine:proton Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Response To Amphetamine Serotonin Secretion By Mast Cell Histamine Secretion By Mast Cell Neurotransmitter Transport Serotonin Transport Chemical Synaptic Transmission Locomotory Behavior Response To Toxic Substance Post-embryonic Development Aminergic Neurotransmitter Loading Into Synaptic Vesicle Monoamine Transport Dopamine Transport Serotonin Uptake Histamine Uptake Establishment Of Localization In Cell Transmembrane Transport Neurotransmitter Loading Into Synaptic Vesicle Somato-dendritic Dopamine Secretion Proton Transmembrane Transport Negative Regulation Of Reactive Oxygen Species Biosynthetic Process
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle
Drugs		Amphetamine Reserpine Norepinephrine Haloperidol Mazindol Benzphetamine Dopamine Deserpidine Ephedra sinica root MMDA Midomafetamine 4-Methoxyamphetamine Dextroamphetamine Metamfetamine Nomifensine Tetrabenazine Histamine Isometheptene Propylhexedrine Serotonin Rauwolfia serpentina root Deutetrabenazine
Diseases
GWAS		Body mass index ( 26426971) Retinopathy x type 2 diabetes interaction ( 32541925) Serum metabolite levels ( 33031748)
Interacting Genes		14 interacting genes: BRICD5 CFHR5 CMTM5 CSNK1A1 CSNK2A1 CSNK2A2 CXCR2 DNAJC5 GPR151 NKG7 SLC61A1 SLC7A1 TMEM109 TOMM6
Entrez ID		6571
HPRD ID		01896
Ensembl ID		ENSG00000165646
Uniprot IDs		Q05940
PDB IDs		8JSW 8JSX 8JT5 8JT9 8JTA 8JTB 8JTC 8T69 8T6A 8T6B 8THR 8UCJ 8UCK 8UCL 8UCM 8UCN 8UCO 8UCP 8WLJ 8WLK 8WLL 8WLM 8WRD 8WRE 8WVG 8X3K 8XO9 8XOA 8XOB 9KQ8 9KQA 9KQE
Enriched GO Terms of Interacting Partners?		Protein Kinase CK2 Complex Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process PcG Protein Complex Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process Negative Regulation Of Programmed Cell Death Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Molybdate Ion Transmembrane Transporter Activity Molybdate Ion Transport Wnt Signaling Pathway Negative Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Response To Stress Interleukin-8 Receptor Activity Interleukin-8-mediated Signaling Pathway Lysine Transport L-histidine Import Across Plasma Membrane Regulation Of Chromosome Separation
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