TOMM6 and SLC16A2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TOMM6	SLC16A2
Description		translocase of outer mitochondrial membrane 6	solute carrier family 16 member 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane TOM Complex	Plasma Membrane Membrane Apical Plasma Membrane
	Molecular Function	Protein Binding	Protein Binding Monocarboxylic Acid Transmembrane Transporter Activity Amino Acid Transmembrane Transporter Activity Thyroid Hormone Transmembrane Transporter Activity Transmembrane Transporter Activity Identical Protein Binding Carboxylic Acid Transmembrane Transporter Activity
	Biological Process	Protein Transport Protein Insertion Into Mitochondrial Outer Membrane	Amino Acid Metabolic Process Thyroid Hormone Generation Monocarboxylic Acid Transport Thyroid Hormone Metabolic Process Transmembrane Transport Thyroid Hormone Transport Thyroid-stimulating Hormone Secretion Amino Acid Import Across Plasma Membrane Transport Across Blood-brain Barrier Carboxylic Acid Transmembrane Transport Negative Regulation Of Neural Precursor Cell Proliferation
Pathways		Mitochondrial protein import PINK1-PRKN Mediated Mitophagy	Organic anion transport by SLCO transporters
Drugs			Pyruvic acid
Diseases			Allan-Herndon-Dudley syndrome; Monocarboxylate transporter 8 deficiency
GWAS		Hip circumference adjusted for BMI ( 34021172)
Interacting Genes		14 interacting genes: AQP6 C1orf159 CD68 CERS4 ERGIC3 FFAR3 GLP1R HUNK ODF4 SEC61A2 SLC10A1 SLC16A2 SLC18A2 TMEM14B	38 interacting genes: ADIPOQ ANKRD46 APOL3 BTN2A2 C3orf52 CCL2 CNIH3 COL4A5 CXCL16 CYB5B EFNA5 FAM3C JAGN1 LAT LEPROTL1 LHFPL5 LPAR3 MFSD6 MS4A13 PLP1 PNLIPRP1 SERPINA7 SLC30A2 SLC38A7 SLC39A13 SLC39A9 SMCO4 SYNGR1 THRA TMEM254 TMEM60 TOMM6 TRARG1 TSPO2 UNC93B1 UPK1B VAMP3 VEGFA
Entrez ID		100188893	6567
HPRD ID		19464	02106
Ensembl ID		ENSG00000214736	ENSG00000147100
Uniprot IDs		Q96B49	P36021
PDB IDs		7CK6 7CP9 7VBY 7VC4 7VD2 7VDD 8XVA 9EIH 9EII 9EIJ
Enriched GO Terms of Interacting Partners?		Post-translational Protein Targeting To Membrane, Translocation Hormone Secretion Hormone Transport Transmembrane Transport Membrane Intracellular Protein Transmembrane Transport Signal Release Nitrate Transmembrane Transporter Activity Glucagon-like Peptide 1 Receptor Activity Negative Regulation Of Blood Pressure Serotonin Secretion By Mast Cell Somato-dendritic Dopamine Secretion Regulation Of Hormone Levels PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Positive Regulation Of Acute Inflammatory Response To Non-antigenic Stimulus Thyroid-stimulating Hormone Secretion Aminergic Neurotransmitter Loading Into Synaptic Vesicle Retrograde Transporter Complex, Golgi To ER Protein Transmembrane Transport Glucagon Receptor Activity Histamine Uptake Serotonin:sodium:chloride Symporter Activity	Membrane Zinc Ion Transport Zinc Ion Transmembrane Transporter Activity Zinc Ion Transmembrane Transport Intracellular Zinc Ion Homeostasis Cytokine Activity Neutrophil Differentiation Myeloid Cell Differentiation Positive Regulation Of Collateral Sprouting Regulation Of Protein Autophosphorylation Positive Regulation Of Cell Growth
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