SLC16A1 and BSG

Number of citations of the paper that reports this interaction (PMID 10921872)
81

Data Source:
HPRD (in vitro, in vivo)

		SLC16A1	BSG
Gene Name		solute carrier family 16 (monocarboxylate transporter), member 1	basigin (Ok blood group)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Centrosome Plasma Membrane Integral Component Of Plasma Membrane Membrane Integral Component Of Membrane Extracellular Vesicular Exosome	Golgi Membrane Acrosomal Membrane Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Sarcolemma Melanosome Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Monocarboxylic Acid Transmembrane Transporter Activity Lactate Transmembrane Transporter Activity Mevalonate Transmembrane Transporter Activity Symporter Activity Secondary Active Monocarboxylate Transmembrane Transporter Activity Protein Homodimerization Activity Organic Cyclic Compound Binding	Protein Binding Mannose Binding
	Biological Process	Pyruvate Metabolic Process Lipid Metabolic Process Blood Coagulation Monocarboxylic Acid Transport Mevalonate Transport Response To Food Plasma Membrane Lactate Transport Glucose Homeostasis Cellular Metabolic Process Small Molecule Metabolic Process Regulation Of Insulin Secretion Leukocyte Migration Centrosome Organization Behavioral Response To Nutrient Transmembrane Transport Cellular Response To Organic Cyclic Compound	Pyruvate Metabolic Process Cell Surface Receptor Signaling Pathway Embryo Implantation Blood Coagulation Extracellular Matrix Disassembly Extracellular Matrix Organization Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Cellular Metabolic Process Small Molecule Metabolic Process Response To Mercury Ion Decidualization Leukocyte Migration Response To CAMP Protein Targeting To Plasma Membrane
Pathways		Pyruvate metabolism Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Pyruvate metabolism and Citric Acid (TCA) cycle The citric acid (TCA) cycle and respiratory electron transport Proton-coupled monocarboxylate transport SLC-mediated transmembrane transport Basigin interactions Cell surface interactions at the vascular wall	Pyruvate metabolism Pyruvate metabolism and Citric Acid (TCA) cycle Integrin cell surface interactions The citric acid (TCA) cycle and respiratory electron transport Degradation of the extracellular matrix Basigin interactions Cell surface interactions at the vascular wall
Drugs		Pyruvic acid
Diseases
GWAS
Protein-Protein Interactions		1 interactors: BSG	10 interactors: CAV1 HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A3 SLC2A4
Entrez ID		6566	682
HPRD ID		02816	00176
Ensembl ID		ENSG00000155380	ENSG00000172270
Uniprot IDs		B4DKS0 P53985	P35613 Q54A51
PDB IDs			3B5H 3I84 3I85 3QQN 3QR2
Enriched GO Terms of Interacting Partners?		Response To Mercury Ion Decidualization Protein Targeting To Plasma Membrane Maternal Placenta Development Embryo Implantation Establishment Of Protein Localization To Plasma Membrane Maternal Process Involved In Female Pregnancy Extracellular Matrix Disassembly Odontogenesis Of Dentin-containing Tooth Response To CAMP Pyruvate Metabolic Process Odontogenesis Protein Localization To Plasma Membrane Response To Organophosphorus Protein Targeting To Membrane Response To Purine-containing Compound Placenta Development Plasma Membrane Organization Leukocyte Migration Establishment Of Protein Localization To Membrane Female Pregnancy	Leukocyte Migration Blood Coagulation Hemostasis Regulation Of Body Fluid Levels Wound Healing Response To Wounding Cell Migration Cell Motility Lactate Transmembrane Transport Plasma Membrane Lactate Transport Lactate Transport Locomotion Movement Of Cell Or Subcellular Component Negative Regulation Of JAK-STAT Cascade Immune System Process Response To Stress Membrane Organization Protein Localization To Membrane Amylopectin Biosynthetic Process Regulation Of Membrane Repolarization During Action Potential Negative Regulation Of Peptidyl-tyrosine Autophosphorylation Uncoating Of Virus Mevalonate Transport Behavioral Response To Nutrient Protein Peptidyl-prolyl Isomerization Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Regulation Of Cellular Localization Regulation Of JAK-STAT Cascade Nitric Oxide Homeostasis Cellular Response To Oxygen Levels Transport Pyruvate Metabolic Process Monocarboxylic Acid Transport Receptor Internalization Involved In Canonical Wnt Signaling Pathway Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Regulation Of Inward Rectifier Potassium Channel Activity Viral Release From Host Cell Viral Process Negative Regulation Of Tyrosine Phosphorylation Of Stat5 Protein Negative Regulation Of Pinocytosis Protein Localization To Plasma Membrane Regulation Of Secretion Caveolin-mediated Endocytosis Protein Localization To Basolateral Plasma Membrane Mammary Gland Involution Protein Localization To Plasma Membrane Raft Positive Regulation Of Metalloenzyme Activity Caveola Assembly Positive Regulation Of Transport Positive Regulation Of Apoptotic Signaling Pathway
Tagcloud ?		2b1 abcc1 abcc4 abcc5 abluminal apposition biotinylated biotinylation choroid ependymal lat1 mct1 microvessel microvessels monocarboxylate oat oatp oatp1a4 oatp2 oatp2b1 oatpb oct3 pgp plexus slc22a8 slc7a5 slco2b1	15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta
Tagcloud (Difference) ?		2b1 abcc1 abcc4 abcc5 abluminal apposition biotinylated biotinylation choroid ependymal lat1 mct1 microvessel microvessels monocarboxylate oat oatp oatp1a4 oatp2 oatp2b1 oatpb oct3 pgp plexus slc22a8 slc7a5 slco2b1	15q24 19q13 20q13 21q21 acquire aggressiveness akt2 angptl4 anoikis cadm2 clustered commonality ctc ctcs dissemination distinctiveness dormancy highlighting intravasation ltbp4 mcrs numbl occult originate plausible signature signatures tff3 tgfbeta
Tagcloud (Intersection) ?