SLC12A4 and CNFN

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC12A4	CNFN
Description		solute carrier family 12 member 4	cornifelin
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Membrane Synapse	Cornified Envelope Cytoplasm
	Molecular Function	Protein Binding ATP Binding Symporter Activity Chloride:monoatomic Cation Symporter Activity Potassium:chloride Symporter Activity Protein Kinase Binding Transmembrane Transporter Activity Protein Serine/threonine Kinase Binding	Protein Binding
	Biological Process	Monoatomic Ion Transport Potassium Ion Transport Cell Volume Homeostasis Chemical Synaptic Transmission Chloride Ion Homeostasis Potassium Ion Homeostasis Transmembrane Transport Potassium Ion Transmembrane Transport Chloride Transmembrane Transport Potassium Ion Import Across Plasma Membrane	Keratinization
Pathways		Cation-coupled Chloride cotransporters
Drugs		Potassium chloride Bumetanide
Diseases
GWAS		Refractive error ( 32231278) Schizophrenia ( 25056061 29483656)
Interacting Genes		10 interacting genes: AP3M1 ATF7IP CNFN CYSRT1 KRTAP12-2 KRTAP19-2 MB21D2 MTNR1B TMEM102 ZNF655	16 interacting genes: CCDC120 CREB5 EVX2 FAM222B HOXA1 HOXB5 HR KPRP SLC12A4 TCF7L2 TFAP2D TLE5 VGLL3 WDR25 ZNF414 ZNF581
Entrez ID		6560	84518
HPRD ID		04987	16729
Ensembl ID		ENSG00000124067	ENSG00000105427
Uniprot IDs		B4DF30 Q9UP95	Q9BYD5
PDB IDs		6KKR 6KKT 6KKU 7AIP 7AIQ 7AIR 7TTH 7TTI
Enriched GO Terms of Interacting Partners?			DNA-binding Transcription Factor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Semicircular Canal Formation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Sequence-specific Double-stranded DNA Binding Abducens Nerve Formation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Optokinetic Behavior Inferior Colliculus Development Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Myoblast Fate Commitment
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