CNFN and VGLL3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNFN	VGLL3
Description		cornifelin	vestigial like family member 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cornified Envelope Cytoplasm	Nucleus
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Keratinization	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS			Adventurousness ( 30643258) Breast cancer ( 29059683) General risk tolerance (MTAG) ( 30643258) HDL cholesterol levels ( 32203549) Hip index ( 34021172) Menarche (age at onset) ( 27182965 21102462) Metabolite levels ( 23823483) Molybdenum levels ( 26025379) Number of sexual partners ( 30643258) Obesity-related traits ( 23251661) Prostate cancer ( 26443449 31562322) Pubertal anthropometrics ( 23449627) Response to TNF inhibitor in rheumatoid arthritis (change in swollen 28-joint count) ( 30166627) Risk-taking tendency (4-domain principal component model) ( 30643258) Smoking status (ever vs never smokers) ( 30643258) Triglyceride levels ( 32203549)
Interacting Genes		16 interacting genes: CCDC120 CREB5 EVX2 FAM222B HOXA1 HOXB5 HR KPRP SLC12A4 TCF7L2 TFAP2D TLE5 VGLL3 WDR25 ZNF414 ZNF581	65 interacting genes: CDPF1 CERCAM CNFN CTRC CYSRT1 DTX2 ESM1 FAM168B FRS3 HGS INCA1 KPRP KRTAP1-1 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP11-1 KRTAP12-1 KRTAP12-2 KRTAP12-3 KRTAP13-2 KRTAP15-1 KRTAP19-1 KRTAP19-2 KRTAP19-6 KRTAP19-7 KRTAP3-1 KRTAP3-3 KRTAP4-11 KRTAP4-2 KRTAP5-11 KRTAP5-6 KRTAP6-1 KRTAP6-2 KRTAP9-2 KRTAP9-3 KRTAP9-8 LASP1 LENG8 MDFI MYO15B OXER1 PCSK5 PITX1 PITX2 PLA2G10 POGZ POU2AF1 PRR22 RBPMS RUSC1 SMARCC1 SMOC1 SPMIP9 TBX15 TEAD1 TEAD2 TEAD3 TEAD4 TRIM42 TSC1 TSPAN4 UFSP1 YPEL3 ZNF34
Entrez ID		84518	389136
HPRD ID		16729	13431
Ensembl ID		ENSG00000105427	ENSG00000206538
Uniprot IDs		Q9BYD5	A8MV65
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA-binding Transcription Factor Activity Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Chromatin DNA Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Semicircular Canal Formation Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Sequence-specific Double-stranded DNA Binding Abducens Nerve Formation RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Optokinetic Behavior Inferior Colliculus Development Beta-catenin-TCF7L2 Complex Catenin-TCF7L2 Complex Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Myoblast Fate Commitment	Intermediate Filament Keratin Filament Hippo Signaling Embryonic Organ Development TEAD-YAP Complex Protein Binding Transcription Regulator Complex
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